Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SALIVB_RS01835 Genome accession   NC_015760
Coordinates   346428..347747 (+) Length   439 a.a.
NCBI ID   WP_013990090.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 341428..352747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS01810 (SALIVB_0360) - 342265..343029 (+) 765 WP_002886634.1 ABC transporter ATP-binding protein -
  SALIVB_RS01815 (SALIVB_0361) - 343029..343739 (+) 711 WP_013990087.1 ABC transporter ATP-binding protein -
  SALIVB_RS01820 (SALIVB_0362) - 343874..344533 (+) 660 WP_013990088.1 CBS and ACT domain-containing protein -
  SALIVB_RS01825 (SALIVB_0363) cysK 344719..345645 (-) 927 WP_002883742.1 cysteine synthase A -
  SALIVB_RS01830 (SALIVB_0364) - 345747..346373 (-) 627 WP_013990089.1 YigZ family protein -
  SALIVB_RS01835 (SALIVB_0365) comFA/cflA 346428..347747 (+) 1320 WP_013990090.1 DEAD/DEAH box helicase Machinery gene
  SALIVB_RS01840 (SALIVB_0366) - 347728..348390 (+) 663 WP_013990091.1 ComF family protein -
  SALIVB_RS01845 (SALIVB_0367) hpf 348469..349017 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50600.52 Da        Isoelectric Point: 9.0046

>NTDB_id=41805 SALIVB_RS01835 WP_013990090.1 346428..347747(+) (comFA/cflA) [Streptococcus salivarius CCHSS3]
MVPKEYYGRLFTKEQLSVDYHSEAFTLESMIKVDKQLRCKRCNSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPALKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
ISLEEQVRLGALEKHHLARRFHGNPLVLPKFFWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=41805 SALIVB_RS01835 WP_013990090.1 346428..347747(+) (comFA/cflA) [Streptococcus salivarius CCHSS3]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGTCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTAACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGCTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTACTTAACAGCGACTTCTACA
ATATCTTTAGAAGAGCAAGTTCGACTTGGAGCTTTAGAAAAACATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTTCTGGCAAGGAAGATTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATATTTTTCCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCTTCAAAAAGCGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376

Multiple sequence alignment