Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H9199_RS11145 Genome accession   NZ_CP060933
Coordinates   2262729..2263385 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2257729..2268385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9199_RS11115 (H9199_11005) dcyD 2258609..2259595 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  H9199_RS11120 (H9199_11010) tcyL 2259610..2260278 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H9199_RS11125 (H9199_11015) tcyN 2260275..2261027 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H9199_RS11130 (H9199_11020) sdiA 2261257..2261979 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  H9199_RS11135 (H9199_11025) yecF 2262046..2262270 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H9199_RS11140 (H9199_11030) yecU 2262257..2262433 (-) 177 WP_001307856.1 protein YecU -
  H9199_RS26090 - 2262516..2262587 (-) 72 Protein_2170 transcriptional regulator -
  H9199_RS11145 (H9199_11035) letA 2262729..2263385 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H9199_RS11150 (H9199_11040) uvrC 2263382..2265214 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  H9199_RS11155 (H9199_11045) pgsA 2265271..2265819 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H9199_RS11175 (H9199_11065) yecA 2266469..2267134 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=418028 H9199_RS11145 WP_000611328.1 2262729..2263385(+) (letA) [Escherichia coli strain EC12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=418028 H9199_RS11145 WP_000611328.1 2262729..2263385(+) (letA) [Escherichia coli strain EC12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482