Detailed information NTG0418023

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S64_RS05510
• Genome accession: NZ_CP047861
• Coordinates: 1092254..1093240 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_1322
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1087254..1098240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S64_RS05485 (E3S64_05485)	-	1087514..1087861 (-)	348	WP_001242103.1	hypothetical protein	-
E3S64_RS05490 (E3S64_05490)	-	1088047..1088640 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S64_RS05495 (E3S64_05495)	-	1088744..1089109 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S64_RS05500 (E3S64_05500)	yjbH	1089132..1089938 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S64_RS05505 (E3S64_05505)	pepF	1090398..1092206 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S64_RS05510 (E3S64_05510)	coiA	1092254..1093240 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S64_RS05515 (E3S64_05515)	mecA	1093361..1094080 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S64_RS05520 (E3S64_05520)	spxA	1094451..1094846 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S64_RS05525 (E3S64_05525)	trpS	1095140..1096129 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S64_RS05530 (E3S64_05530)	opp4C	1096171..1097052 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S64_RS05535 (E3S64_05535)	opp4B	1097064..1098026 (-)	963	WP_160199664.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418023 E3S64_RS05510 WP_000959282.1 1092254..1093240(-) (coiA) [Staphylococcus aureus strain UP_1322]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418023 E3S64_RS05510 WP_000959282.1 1092254..1093240(-) (coiA) [Staphylococcus aureus strain UP_1322]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976