Detailed information NTG0417892

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S68_RS05255
• Genome accession: NZ_CP047854
• Coordinates: 1057749..1058735 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_1525
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1052749..1063735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S68_RS05230 (E3S68_05230)	-	1053009..1053356 (-)	348	WP_001242103.1	hypothetical protein	-
E3S68_RS05235 (E3S68_05235)	-	1053542..1054135 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S68_RS05240 (E3S68_05240)	-	1054239..1054604 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S68_RS05245 (E3S68_05245)	yjbH	1054627..1055433 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S68_RS05250 (E3S68_05250)	pepF	1055893..1057701 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S68_RS05255 (E3S68_05255)	coiA	1057749..1058735 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S68_RS05260 (E3S68_05260)	mecA	1058856..1059575 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S68_RS05265 (E3S68_05265)	spxA	1059946..1060341 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S68_RS05270 (E3S68_05270)	trpS	1060634..1061623 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S68_RS05275 (E3S68_05275)	opp4C	1061665..1062546 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S68_RS05280 (E3S68_05280)	opp4B	1062558..1063520 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=417892 E3S68_RS05255 WP_000959282.1 1057749..1058735(-) (coiA) [Staphylococcus aureus strain UP_1525]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=417892 E3S68_RS05255 WP_000959282.1 1057749..1058735(-) (coiA) [Staphylococcus aureus strain UP_1525]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976