Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H9205_RS09690 Genome accession   NZ_CP060902
Coordinates   2021557..2022213 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC20     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016557..2027213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9205_RS09660 (H9205_09605) dcyD 2017436..2018422 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  H9205_RS09665 (H9205_09610) tcyL 2018437..2019105 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H9205_RS09670 (H9205_09615) tcyN 2019102..2019854 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H9205_RS09675 (H9205_09620) sdiA 2020084..2020806 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  H9205_RS09680 (H9205_09625) yecF 2020874..2021098 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H9205_RS09685 (H9205_09630) yecU 2021085..2021261 (-) 177 WP_000590347.1 protein YecU -
  H9205_RS24970 - 2021344..2021415 (-) 72 Protein_1900 transcriptional regulator -
  H9205_RS09690 (H9205_09635) letA 2021557..2022213 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H9205_RS09695 (H9205_09640) uvrC 2022210..2024042 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  H9205_RS09700 (H9205_09645) pgsA 2024099..2024647 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H9205_RS09720 (H9205_09665) yecA 2025297..2025962 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=417536 H9205_RS09690 WP_000611335.1 2021557..2022213(+) (letA) [Escherichia coli strain EC20]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=417536 H9205_RS09690 WP_000611335.1 2021557..2022213(+) (letA) [Escherichia coli strain EC20]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment