Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IAI02_RS09505 Genome accession   NZ_CP060748
Coordinates   1979355..1980011 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC96     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1974355..1985011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAI02_RS09475 (IAI02_09470) dcyD 1975235..1976221 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  IAI02_RS09480 (IAI02_09475) tcyL 1976236..1976904 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IAI02_RS09485 (IAI02_09480) tcyN 1976901..1977653 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IAI02_RS09490 (IAI02_09485) sdiA 1977883..1978605 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  IAI02_RS09495 (IAI02_09490) yecF 1978672..1978896 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IAI02_RS09500 (IAI02_09495) yecU 1978883..1979059 (-) 177 WP_000590347.1 protein YecU -
  IAI02_RS24720 - 1979142..1979213 (-) 72 Protein_1877 transcriptional regulator -
  IAI02_RS09505 (IAI02_09500) letA 1979355..1980011 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IAI02_RS09510 (IAI02_09505) uvrC 1980008..1981840 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IAI02_RS09515 (IAI02_09510) pgsA 1981897..1982445 (+) 549 WP_057102527.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IAI02_RS09535 (IAI02_09530) yecA 1983095..1983760 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=416970 IAI02_RS09505 WP_000611335.1 1979355..1980011(+) (letA) [Escherichia coli strain EC96]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=416970 IAI02_RS09505 WP_000611335.1 1979355..1980011(+) (letA) [Escherichia coli strain EC96]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486