Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E3S67_RS12145 Genome accession   NZ_CP047802
Coordinates   2384642..2385307 (-) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain UP_1442     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2379642..2390307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S67_RS12125 (E3S67_12125) - 2380112..2380225 (-) 114 Protein_2348 hypothetical protein -
  E3S67_RS12130 (E3S67_12130) - 2380884..2382884 (-) 2001 WP_000776750.1 ABC transporter permease -
  E3S67_RS12135 (E3S67_12135) - 2382881..2383636 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  E3S67_RS12140 (E3S67_12140) braS 2383744..2384631 (-) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E3S67_RS12145 (E3S67_12145) braR 2384642..2385307 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E3S67_RS12150 (E3S67_12150) - 2385333..2385533 (-) 201 WP_000604730.1 hypothetical protein -
  E3S67_RS12155 (E3S67_12155) - 2385731..2387155 (+) 1425 WP_000953755.1 alkaline phosphatase -
  E3S67_RS14645 - 2387215..2387316 (-) 102 WP_000731976.1 SE2200 family small protein -
  E3S67_RS12165 (E3S67_12165) - 2387438..2387893 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E3S67_RS12170 (E3S67_12170) - 2388138..2388899 (-) 762 WP_000323441.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=416816 E3S67_RS12145 WP_000697877.1 2384642..2385307(-) (braR) [Staphylococcus aureus strain UP_1442]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=416816 E3S67_RS12145 WP_000697877.1 2384642..2385307(-) (braR) [Staphylococcus aureus strain UP_1442]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment