Detailed information NTG0416815

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S67_RS12140
• Genome accession: NZ_CP047802
• Coordinates: 2383744..2384631 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UP_1442
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2378744..2389631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S67_RS12110 (E3S67_12110)	-	2378763..2378855 (+)	93	WP_010956583.1	hypothetical protein	-
E3S67_RS12115 (E3S67_12115)	-	2378963..2379460 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3S67_RS12120 (E3S67_12120)	-	2379470..2379730 (-)	261	WP_001791974.1	hypothetical protein	-
E3S67_RS12125 (E3S67_12125)	-	2380112..2380225 (-)	114	Protein_2348	hypothetical protein	-
E3S67_RS12130 (E3S67_12130)	-	2380884..2382884 (-)	2001	WP_000776750.1	ABC transporter permease	-
E3S67_RS12135 (E3S67_12135)	-	2382881..2383636 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S67_RS12140 (E3S67_12140)	braS	2383744..2384631 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S67_RS12145 (E3S67_12145)	braR	2384642..2385307 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S67_RS12150 (E3S67_12150)	-	2385333..2385533 (-)	201	WP_000604730.1	hypothetical protein	-
E3S67_RS12155 (E3S67_12155)	-	2385731..2387155 (+)	1425	WP_000953755.1	alkaline phosphatase	-
E3S67_RS14645	-	2387215..2387316 (-)	102	WP_000731976.1	SE2200 family small protein	-
E3S67_RS12165 (E3S67_12165)	-	2387438..2387893 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S67_RS12170 (E3S67_12170)	-	2388138..2388899 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=416815 E3S67_RS12140 WP_000143425.1 2383744..2384631(-) (braS) [Staphylococcus aureus strain UP_1442]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=416815 E3S67_RS12140 WP_000143425.1 2383744..2384631(-) (braS) [Staphylococcus aureus strain UP_1442]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1