Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H9445_RS10895 Genome accession   NZ_CP060709
Coordinates   2156947..2157603 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ST18     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2151947..2162603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9445_RS10865 (H9445_10865) yecA 2153198..2153863 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  H9445_RS10885 (H9445_10885) pgsA 2154513..2155061 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H9445_RS10890 (H9445_10890) uvrC 2155118..2156950 (-) 1833 WP_001283395.1 excinuclease ABC subunit UvrC Machinery gene
  H9445_RS10895 (H9445_10895) letA 2156947..2157603 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H9445_RS24040 - 2157745..2157816 (+) 72 Protein_2169 transcriptional regulator -
  H9445_RS10900 (H9445_10900) yecU 2157899..2158075 (+) 177 WP_000590347.1 protein YecU -
  H9445_RS10905 (H9445_10905) yecF 2158062..2158286 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  H9445_RS10910 (H9445_10910) sdiA 2158354..2159076 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  H9445_RS10915 (H9445_10915) tcyN 2159306..2160058 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H9445_RS10920 (H9445_10920) tcyL 2160055..2160723 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  H9445_RS10925 (H9445_10925) dcyD 2160738..2161724 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=416802 H9445_RS10895 WP_000611335.1 2156947..2157603(-) (letA) [Escherichia coli strain ST18]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=416802 H9445_RS10895 WP_000611335.1 2156947..2157603(-) (letA) [Escherichia coli strain ST18]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486