Detailed information NTG0416594

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S77_RS05480
• Genome accession: NZ_CP047797
• Coordinates: 1109788..1110774 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959278.1
• Uniprot ID: A0A6B5F529
• Organism: Staphylococcus aureus strain UP_426
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1104788..1115774

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S77_RS05455 (E3S77_05455)	-	1105047..1105394 (-)	348	WP_001242107.1	hypothetical protein	-
E3S77_RS05460 (E3S77_05460)	-	1105580..1106173 (+)	594	WP_000224616.1	CYTH domain-containing protein	-
E3S77_RS05465 (E3S77_05465)	-	1106277..1106642 (+)	366	WP_000214067.1	truncated hemoglobin YjbI	-
E3S77_RS05470 (E3S77_05470)	yjbH	1106665..1107471 (+)	807	WP_000896694.1	protease adaptor protein YjbH	-
E3S77_RS05475 (E3S77_05475)	pepF	1107932..1109740 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S77_RS05480 (E3S77_05480)	coiA	1109788..1110774 (-)	987	WP_000959278.1	competence protein CoiA	Machinery gene
E3S77_RS05485 (E3S77_05485)	mecA	1110895..1111614 (-)	720	WP_001217727.1	adaptor protein MecA	-
E3S77_RS05490 (E3S77_05490)	spxA	1111995..1112390 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S77_RS05495 (E3S77_05495)	trpS	1112685..1113674 (+)	990	WP_000448929.1	tryptophan--tRNA ligase	-
E3S77_RS05500 (E3S77_05500)	opp4C	1113716..1114597 (-)	882	WP_001180269.1	oligopeptide ABC transporter permease	-
E3S77_RS05505 (E3S77_05505)	opp4B	1114609..1115571 (-)	963	WP_000593417.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38679.31 Da
• Isoelectric Point: 9.5882

>NTDB_id=416594 E3S77_RS05480 WP_000959278.1 1109788..1110774(-) (coiA) [Staphylococcus aureus strain UP_426]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKGNAKISELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTVQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLLSDNLNYFKLKKFIVALDSKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=416594 E3S77_RS05480 WP_000959278.1 1109788..1110774(-) (coiA) [Staphylococcus aureus strain UP_426]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTTAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAGGGAATGCCAAAATTAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTTG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAGTTACAG
TTAACTGTTCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTACTAAGTGACAATCTTAATTATTTTAAACTGAAAA
AGTTTATTGTTGCTCTAGATAGCAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-288)

3D structure

• AlphaFold DB: A0A6B5F529

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	96.646	100	0.966
coiA	Staphylococcus aureus MW2	96.646	100	0.966