Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E3S78_RS13365 Genome accession   NZ_CP047796
Coordinates   2727792..2728478 (+) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain UP_462     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2722792..2733478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S78_RS13330 (E3S78_13330) yqeH 2723319..2724419 (+) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -
  E3S78_RS13335 (E3S78_13335) aroE 2724433..2725239 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  E3S78_RS13340 (E3S78_13340) yhbY 2725243..2725533 (+) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  E3S78_RS13345 (E3S78_13345) nadD 2725536..2726105 (+) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E3S78_RS13350 (E3S78_13350) yqeK 2726095..2726679 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E3S78_RS13355 (E3S78_13355) rsfS 2726680..2727033 (+) 354 WP_001088020.1 ribosome silencing factor -
  E3S78_RS13360 (E3S78_13360) - 2727036..2727752 (+) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  E3S78_RS13365 (E3S78_13365) comEA 2727792..2728478 (+) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  E3S78_RS13370 (E3S78_13370) - 2728570..2729031 (+) 462 WP_000439692.1 ComE operon protein 2 -
  E3S78_RS13375 (E3S78_13375) comEC 2729036..2731237 (+) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E3S78_RS13380 (E3S78_13380) holA 2731294..2732268 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -
  E3S78_RS13385 (E3S78_13385) rpsT 2732313..2732564 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=416561 E3S78_RS13365 WP_001794049.1 2727792..2728478(+) (comEA) [Staphylococcus aureus strain UP_462]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=416561 E3S78_RS13365 WP_001794049.1 2727792..2728478(+) (comEA) [Staphylococcus aureus strain UP_462]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment