Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   H7786_RS04455 Genome accession   NZ_CP060649
Coordinates   883938..885734 (+) Length   598 a.a.
NCBI ID   WP_030125956.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 878938..890734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7786_RS04440 (H7786_04480) - 880497..881285 (+) 789 WP_002984836.1 response regulator transcription factor -
  H7786_RS04445 (H7786_04485) - 881279..882325 (+) 1047 WP_011017728.1 extracellular solute-binding protein -
  H7786_RS04450 (H7786_04490) - 882440..883837 (+) 1398 WP_030125957.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  H7786_RS04455 (H7786_04495) uvrC 883938..885734 (+) 1797 WP_030125956.1 excinuclease ABC subunit UvrC Machinery gene
  H7786_RS04460 (H7786_04500) - 885919..886521 (+) 603 WP_002989923.1 nitroreductase family protein -
  H7786_RS04465 (H7786_04505) pepV 886646..888055 (+) 1410 WP_030125955.1 dipeptidase PepV -
  H7786_RS04470 (H7786_04510) mnmE 888123..889499 (-) 1377 WP_030125954.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  H7786_RS04475 (H7786_04515) rplJ 889833..890333 (+) 501 WP_002984821.1 50S ribosomal protein L10 -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68953.74 Da        Isoelectric Point: 9.6619

>NTDB_id=416547 H7786_RS04455 WP_030125956.1 883938..885734(+) (uvrC) [Streptococcus pyogenes strain TSPY270]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEIN
LIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALANKNARVSLQQKFDLLEKDIKKTSGAIENLGHLLRIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=416547 H7786_RS04455 WP_030125956.1 883938..885734(+) (uvrC) [Streptococcus pyogenes strain TSPY270]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCTAAGAATTTGAAAAAACGCGTCCGGTCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AGTTACTAGTATCTGAGATTGTAGATTTCGAATATATTGTAACAGAGTCAGATACCGAAGCGCTTTTGTTGGAAATTAAC
TTGATTCAAAAAAATATGCCTAAGTACAACATCAAGTTAAAAGATGATAAATCTTATCCCTTTCTCAAAATCACAAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGATTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATGT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGATCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCTACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GATTTGCAAGATAGAGATATCTTTGGCTATTATGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCCAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTAATAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCATTTACTTA
GGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGTCCAGTTGCGGCTATGGTTGTT
TTTGTTGATGGCAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAGTCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAGCACCAGACCCATGATTTGCTTTTTGGAAACCCACTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTGCGACGTAAAAATT
CTTTTTCATCAACATTAGATCATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

73.684

98.495

0.726
  uvrC Streptococcus pneumoniae TIGR4

73.684

98.495

0.726
  uvrC Streptococcus pneumoniae D39

73.684

98.495

0.726