Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E3S87_RS02175 Genome accession   NZ_CP047793
Coordinates   408725..409411 (+) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain UP_764     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 399714..413201 408725..409411 within 0


Gene organization within MGE regions


Location: 399714..413201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S87_RS02115 (E3S87_02115) - 399714..400933 (+) 1220 Protein_385 Fic family protein -
  E3S87_RS02120 (E3S87_02120) - 401481..402233 (+) 753 Protein_386 exotoxin OB-fold domain-containing protein -
  E3S87_RS02125 (E3S87_02125) - 402435..402704 (-) 270 WP_000829750.1 hypothetical protein -
  E3S87_RS02130 (E3S87_02130) mtnN 403018..403704 (+) 687 WP_000579273.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase -
  E3S87_RS02135 (E3S87_02135) - 403724..404251 (+) 528 WP_000524902.1 YqeG family HAD IIIA-type phosphatase -
  E3S87_RS02140 (E3S87_02140) yqeH 404252..405352 (+) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -
  E3S87_RS02145 (E3S87_02145) aroE 405366..406172 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  E3S87_RS02150 (E3S87_02150) yhbY 406176..406466 (+) 291 WP_160175414.1 ribosome assembly RNA-binding protein YhbY -
  E3S87_RS02155 (E3S87_02155) nadD 406469..407038 (+) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E3S87_RS02160 (E3S87_02160) yqeK 407028..407612 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E3S87_RS02165 (E3S87_02165) rsfS 407613..407966 (+) 354 WP_001088020.1 ribosome silencing factor -
  E3S87_RS02170 (E3S87_02170) - 407969..408685 (+) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  E3S87_RS02175 (E3S87_02175) comEA 408725..409411 (+) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  E3S87_RS02180 (E3S87_02180) - 409503..409964 (+) 462 WP_000439692.1 ComE operon protein 2 -
  E3S87_RS02185 (E3S87_02185) comEC 409969..412170 (+) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E3S87_RS02190 (E3S87_02190) holA 412227..413201 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=416413 E3S87_RS02175 WP_001794049.1 408725..409411(+) (comEA) [Staphylococcus aureus strain UP_764]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=416413 E3S87_RS02175 WP_001794049.1 408725..409411(+) (comEA) [Staphylococcus aureus strain UP_764]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment