Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   E3S99_RS02385 Genome accession   NZ_CP047785
Coordinates   423753..425954 (+) Length   733 a.a.
NCBI ID   WP_001622275.1    Uniprot ID   A0A0U1MM33
Organism   Staphylococcus aureus strain UP_1186     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 418753..430954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S99_RS02345 (E3S99_02345) aroE 419150..419956 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  E3S99_RS02350 (E3S99_02350) yhbY 419960..420250 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  E3S99_RS02355 (E3S99_02355) nadD 420253..420822 (+) 570 WP_000725165.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E3S99_RS02360 (E3S99_02360) yqeK 420812..421396 (+) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E3S99_RS02365 (E3S99_02365) rsfS 421397..421750 (+) 354 WP_001088020.1 ribosome silencing factor -
  E3S99_RS02370 (E3S99_02370) - 421753..422469 (+) 717 WP_000084840.1 class I SAM-dependent DNA methyltransferase -
  E3S99_RS02375 (E3S99_02375) comEA 422509..423195 (+) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  E3S99_RS02380 (E3S99_02380) - 423287..423748 (+) 462 WP_000439693.1 ComE operon protein 2 -
  E3S99_RS02385 (E3S99_02385) comEC 423753..425954 (+) 2202 WP_001622275.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E3S99_RS02390 (E3S99_02390) holA 426011..426985 (+) 975 WP_001282573.1 DNA polymerase III subunit delta -
  E3S99_RS02395 (E3S99_02395) rpsT 427030..427281 (-) 252 WP_001274017.1 30S ribosomal protein S20 -
  E3S99_RS02400 (E3S99_02400) lepA 427627..429450 (+) 1824 WP_000368338.1 translation elongation factor 4 -

Sequence

Protein


Download         Length: 733 a.a.        Molecular weight: 85048.20 Da        Isoelectric Point: 10.0564

>NTDB_id=416079 E3S99_RS02385 WP_001622275.1 423753..425954(+) (comEC) [Staphylococcus aureus strain UP_1186]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVLLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITLPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVFDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNEYLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYRNASGL

Nucleotide


Download         Length: 2202 bp        

>NTDB_id=416079 E3S99_RS02385 WP_001622275.1 423753..425954(+) (comEC) [Staphylococcus aureus strain UP_1186]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTACTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGATTAAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAAATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAAATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTATTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAACTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CGCTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTGCTTTTCCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACTTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGCTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGACAAGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTATTGATTGATACAGGTGGGAAAGTGTTTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGTTAAATGAAAGAGGGATAAATGAATTAGAGTACCTAATTTTAACACATC
CACACAATGACCATATTGGCGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAAGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTGTTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATATTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATAGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(474-679)

Competence protein (Competence)

(183-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1MM33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Staphylococcus aureus N315

98.636

100

0.986
  comEC Staphylococcus aureus MW2

98.499

100

0.985

Multiple sequence alignment