Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E3T00_RS12740 Genome accession   NZ_CP047784
Coordinates   2587235..2587900 (-) Length   221 a.a.
NCBI ID   WP_000697879.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_1209     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2582235..2592900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T00_RS12720 (E3T00_12720) - 2582704..2582817 (-) 114 WP_011447078.1 hypothetical protein -
  E3T00_RS12725 (E3T00_12725) - 2583476..2585476 (-) 2001 WP_043044900.1 ABC transporter permease -
  E3T00_RS12730 (E3T00_12730) - 2585473..2586228 (-) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  E3T00_RS12735 (E3T00_12735) braS 2586337..2587224 (-) 888 WP_043044899.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E3T00_RS12740 (E3T00_12740) braR 2587235..2587900 (-) 666 WP_000697879.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E3T00_RS12745 (E3T00_12745) - 2587926..2588126 (-) 201 WP_000604727.1 hypothetical protein -
  E3T00_RS12750 (E3T00_12750) - 2588324..2589748 (+) 1425 WP_000953744.1 alkaline phosphatase -
  E3T00_RS13435 - 2589808..2589909 (-) 102 WP_000731972.1 SE2200 family small protein -
  E3T00_RS12760 (E3T00_12760) - 2590031..2590486 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E3T00_RS12765 (E3T00_12765) - 2590731..2591492 (-) 762 WP_043044898.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25388.46 Da        Isoelectric Point: 4.7961

>NTDB_id=416067 E3T00_RS12740 WP_000697879.1 2587235..2587900(-) (braR) [Staphylococcus aureus strain UP_1209]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=416067 E3T00_RS12740 WP_000697879.1 2587235..2587900(-) (braR) [Staphylococcus aureus strain UP_1209]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATATTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment