Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H7792_RS04830 Genome accession   NZ_CP060643
Coordinates   989555..990031 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain TSPY416     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 984555..995031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS04815 (H7792_04815) fbp54 985367..987019 (+) 1653 WP_228650288.1 Rqc2 family fibronectin-binding protein Fbp54 -
  H7792_RS04820 (H7792_04820) - 987079..988326 (-) 1248 WP_111713816.1 tetratricopeptide repeat protein -
  H7792_RS04825 (H7792_04825) - 988316..989497 (-) 1182 WP_002990002.1 AI-2E family transporter -
  H7792_RS04830 (H7792_04830) mutX 989555..990031 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  H7792_RS04835 (H7792_04835) prx 990439..990627 (-) 189 WP_136022789.1 Paratox Regulator
  H7792_RS04840 (H7792_04840) spel 990742..991530 (-) 789 WP_020833516.1 streptococcal pyrogenic exotoxin SpeL -
  H7792_RS04845 (H7792_04845) spem 991812..992525 (-) 714 WP_014635497.1 streptococcal pyrogenic exotoxin SpeM -
  H7792_RS04850 (H7792_04850) - 992881..994086 (-) 1206 WP_136115266.1 Fic family protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=415992 H7792_RS04830 WP_002984880.1 989555..990031(-) (mutX) [Streptococcus pyogenes strain TSPY416]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=415992 H7792_RS04830 WP_002984880.1 989555..990031(-) (mutX) [Streptococcus pyogenes strain TSPY416]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCTTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment