Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   H7792_RS04610 Genome accession   NZ_CP060643
Coordinates   934365..936161 (-) Length   598 a.a.
NCBI ID   WP_111713797.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 929365..941161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS04590 (H7792_04590) rplJ 929764..930264 (-) 501 WP_002984821.1 50S ribosomal protein L10 -
  H7792_RS04595 (H7792_04595) mnmE 930600..931976 (+) 1377 WP_111713795.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  H7792_RS04600 (H7792_04600) pepV 932044..933453 (-) 1410 WP_063631355.1 dipeptidase PepV -
  H7792_RS04605 (H7792_04605) - 933578..934180 (-) 603 WP_111713796.1 nitroreductase family protein -
  H7792_RS04610 (H7792_04610) uvrC 934365..936161 (-) 1797 WP_111713797.1 excinuclease ABC subunit UvrC Machinery gene
  H7792_RS04615 (H7792_04615) - 936263..937660 (-) 1398 WP_111713798.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  H7792_RS04620 (H7792_04620) - 937775..938821 (-) 1047 WP_002984833.1 extracellular solute-binding protein -
  H7792_RS04625 (H7792_04625) - 938815..939603 (-) 789 WP_002984836.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68917.74 Da        Isoelectric Point: 9.6587

>NTDB_id=415991 H7792_RS04610 WP_111713797.1 934365..936161(-) (uvrC) [Streptococcus pyogenes strain TSPY416]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEIN
LIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDIKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=415991 H7792_RS04610 WP_111713797.1 934365..936161(-) (uvrC) [Streptococcus pyogenes strain TSPY416]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCCAAGAATTTGAAAAAACGCGTCCGGTCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AGTTATTAGTATCTGAGATTGTAGATTTCGAATATATTGTAACAGAGTCAGATACCGAAGCGCTTTTGTTGGAAATTAAC
TTGATTCAAAAAAATATGCCTAAGTACAACATCAAGTTAAAAGATGATAAATCTTATCCCTTTCTCAAAATCACAAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGATTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATAT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGATCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GATTTGCAAGATAGAGATATCTTTGGCTATTATGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCCAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTACTAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCAGTTACTTA
AGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGTCCAGTTGCGGCTATGGTTGTT
TTTGTTGATGGCAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAGTCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAGCACCAGACCCATGATTTGCTTTTTGGAAACCCACTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTGCGACGTAAAAATT
CTTTTTCATCAACATTAGATCATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

73.514

98.495

0.724
  uvrC Streptococcus pneumoniae TIGR4

73.514

98.495

0.724
  uvrC Streptococcus pneumoniae D39

73.514

98.495

0.724