Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H7792_RS02605 Genome accession   NZ_CP060643
Coordinates   507295..507936 (+) Length   213 a.a.
NCBI ID   WP_002991888.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 502295..512936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS02585 (H7792_02570) - 502852..503592 (+) 741 WP_002983660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H7792_RS02590 (H7792_02575) pknB 503589..505487 (+) 1899 WP_228650373.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H7792_RS02595 (H7792_02580) liaF 505609..506301 (+) 693 WP_011054833.1 cell wall-active antibiotics response protein LiaF -
  H7792_RS02600 (H7792_02585) - 506298..507302 (+) 1005 WP_002991890.1 sensor histidine kinase -
  H7792_RS02605 (H7792_02590) vraR 507295..507936 (+) 642 WP_002991888.1 response regulator transcription factor Regulator
  H7792_RS02610 (H7792_02595) - 507973..509373 (+) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H7792_RS02615 (H7792_02600) - 509373..509750 (+) 378 WP_023610575.1 S1 RNA-binding domain-containing protein -
  H7792_RS02620 (H7792_02605) cysK 509768..510709 (-) 942 WP_009880467.1 cysteine synthase A -
  H7792_RS02625 (H7792_02610) - 510837..511469 (-) 633 WP_009880468.1 YigZ family protein -
  H7792_RS02630 (H7792_02615) comFA/cflA 511525..512850 (+) 1326 WP_111713664.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23767.50 Da        Isoelectric Point: 5.1640

>NTDB_id=415971 H7792_RS02605 WP_002991888.1 507295..507936(+) (vraR) [Streptococcus pyogenes strain TSPY416]
MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTCSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=415971 H7792_RS02605 WP_002991888.1 507295..507936(+) (vraR) [Streptococcus pyogenes strain TSPY416]
ATGAGTAAGATAAAAGTGATATTGGTCGATGATCATGAAATGGTCCGCATGGGACTCAAGAGTTTTTTGAATTTACAAGC
TGATATTGATGTCGTTGGTGAAGCCTCTAATGGACGTGAAGGGGTTGATTTGGCATTGGCCTTGAAGCCAGATGTTTTGG
TTATGGATCTAGTGATGCCAGAGTTAGGCGGTGTTGAGGCAACTTTAGAAGTCCTAAAAAAATGGAAAGAGGCTAAGGTA
CTTGTGTTAACTTCCTATCTAGATAATGAAAAGATATACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTGTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAAGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCATGAGGAACTAACAGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACCCAAGCGGTTGTCTATGCTTTTCGACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

96.714

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385