Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E3T04_RS06960 Genome accession   NZ_CP047782
Coordinates   1400768..1401454 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain UP_1352     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1395768..1406454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T04_RS06940 (E3T04_06940) rpsT 1396682..1396933 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  E3T04_RS06945 (E3T04_06945) holA 1396978..1397952 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  E3T04_RS06950 (E3T04_06950) comEC 1398009..1400210 (-) 2202 WP_000967508.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E3T04_RS06955 (E3T04_06955) - 1400215..1400676 (-) 462 WP_000439692.1 ComE operon protein 2 -
  E3T04_RS06960 (E3T04_06960) comEA 1400768..1401454 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  E3T04_RS06965 (E3T04_06965) - 1401494..1402210 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  E3T04_RS06970 (E3T04_06970) rsfS 1402213..1402566 (-) 354 WP_001088020.1 ribosome silencing factor -
  E3T04_RS06975 (E3T04_06975) yqeK 1402567..1403151 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E3T04_RS06980 (E3T04_06980) nadD 1403141..1403710 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E3T04_RS06985 (E3T04_06985) yhbY 1403713..1404003 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  E3T04_RS06990 (E3T04_06990) aroE 1404007..1404813 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  E3T04_RS06995 (E3T04_06995) yqeH 1404827..1405927 (-) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=415968 E3T04_RS06960 WP_001794049.1 1400768..1401454(-) (comEA) [Staphylococcus aureus strain UP_1352]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=415968 E3T04_RS06960 WP_001794049.1 1400768..1401454(-) (comEA) [Staphylococcus aureus strain UP_1352]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment