Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E3T11_RS12845 Genome accession   NZ_CP047780
Coordinates   2626025..2626711 (+) Length   228 a.a.
NCBI ID   WP_001788928.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_1539     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2621025..2631711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T11_RS12810 (E3T11_12810) yqeH 2621552..2622652 (+) 1101 WP_001280136.1 ribosome biogenesis GTPase YqeH -
  E3T11_RS12815 (E3T11_12815) aroE 2622666..2623472 (+) 807 WP_000666744.1 shikimate dehydrogenase -
  E3T11_RS12820 (E3T11_12820) yhbY 2623476..2623766 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E3T11_RS12825 (E3T11_12825) nadD 2623769..2624338 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E3T11_RS12830 (E3T11_12830) yqeK 2624328..2624912 (+) 585 WP_001019326.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E3T11_RS12835 (E3T11_12835) rsfS 2624913..2625266 (+) 354 WP_001088020.1 ribosome silencing factor -
  E3T11_RS12840 (E3T11_12840) - 2625269..2625985 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E3T11_RS12845 (E3T11_12845) comEA 2626025..2626711 (+) 687 WP_001788928.1 ComEA family DNA-binding protein Machinery gene
  E3T11_RS12850 (E3T11_12850) - 2626803..2627264 (+) 462 WP_000439693.1 ComE operon protein 2 -
  E3T11_RS12855 (E3T11_12855) comEC 2627269..2629470 (+) 2202 WP_001641560.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E3T11_RS12860 (E3T11_12860) holA 2629527..2630501 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  E3T11_RS12865 (E3T11_12865) rpsT 2630546..2630797 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25888.59 Da        Isoelectric Point: 9.6751

>NTDB_id=415892 E3T11_RS12845 WP_001788928.1 2626025..2626711(+) (comEA) [Staphylococcus aureus strain UP_1539]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=415892 E3T11_RS12845 WP_001788928.1 2626025..2626711(+) (comEA) [Staphylococcus aureus strain UP_1539]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

99.561

0.996
  comEA Staphylococcus aureus MW2

97.357

99.561

0.969

Multiple sequence alignment