Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   E3T12_RS01295 Genome accession   NZ_CP047779
Coordinates   245724..246293 (+) Length   189 a.a.
NCBI ID   WP_000872867.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_1559     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 240724..251293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T12_RS01270 (E3T12_01270) cysE 241937..242584 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  E3T12_RS01275 (E3T12_01275) cysS 242568..243968 (+) 1401 WP_000631982.1 cysteine--tRNA ligase -
  E3T12_RS01280 (E3T12_01280) - 243961..244365 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  E3T12_RS01285 (E3T12_01285) rlmB 244373..245119 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  E3T12_RS01290 (E3T12_01290) - 245119..245643 (+) 525 WP_000664740.1 NYN domain-containing protein -
  E3T12_RS01295 (E3T12_01295) sigH 245724..246293 (+) 570 WP_000872867.1 sigma-70 family RNA polymerase sigma factor Regulator
  E3T12_RS01300 (E3T12_01300) rpmG 246408..246551 (+) 144 WP_001791441.1 50S ribosomal protein L33 -
  E3T12_RS01305 (E3T12_01305) secE 246607..246789 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  E3T12_RS01310 (E3T12_01310) nusG 246802..247350 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  E3T12_RS01315 (E3T12_01315) rplK 247531..247953 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  E3T12_RS01320 (E3T12_01320) rplA 248161..248850 (+) 690 WP_001074620.1 50S ribosomal protein L1 -
  E3T12_RS01330 (E3T12_01330) rplJ 249125..249625 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  E3T12_RS01335 (E3T12_01335) rplL 249668..250036 (+) 369 WP_001273587.1 50S ribosomal protein L7/L12 -
  E3T12_RS01340 (E3T12_01340) - 250211..250819 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23111.98 Da        Isoelectric Point: 9.6015

>NTDB_id=415821 E3T12_RS01295 WP_000872867.1 245724..246293(+) (sigH) [Staphylococcus aureus strain UP_1559]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSAEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=415821 E3T12_RS01295 WP_000872867.1 245724..246293(+) (sigH) [Staphylococcus aureus strain UP_1559]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATACGGCGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGATTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGCAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment