Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   HUG14_RS05750 Genome accession   NZ_CP060580
Coordinates   1166276..1167718 (-) Length   480 a.a.
NCBI ID   WP_010905315.1    Uniprot ID   Q9CIG6
Organism   Lactococcus lactis strain K_LL005     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1161276..1172718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUG14_RS05725 (HUG14_05725) nox 1161309..1162649 (+) 1341 WP_023188995.1 H2O-forming NADH oxidase -
  HUG14_RS05730 (HUG14_05730) - 1162739..1163128 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  HUG14_RS05735 (HUG14_05735) groES 1163248..1163532 (+) 285 WP_003131589.1 co-chaperone GroES -
  HUG14_RS05740 (HUG14_05740) groL 1163620..1165248 (+) 1629 WP_109990650.1 chaperonin GroEL -
  HUG14_RS05745 (HUG14_05745) vicX 1165295..1166107 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  HUG14_RS05750 (HUG14_05750) vicK 1166276..1167718 (-) 1443 WP_010905315.1 cell wall metabolism sensor histidine kinase WalK Regulator
  HUG14_RS05755 (HUG14_05755) yycF 1167711..1168412 (-) 702 WP_003131580.1 response regulator YycF -
  HUG14_RS05760 (HUG14_05760) tmk 1168590..1169225 (+) 636 WP_012897230.1 dTMP kinase -
  HUG14_RS05765 (HUG14_05765) - 1169358..1170218 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  HUG14_RS05770 (HUG14_05770) yaaT 1170270..1171052 (+) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  HUG14_RS05775 (HUG14_05775) yabA 1171045..1171371 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  HUG14_RS05780 (HUG14_05780) rsmI 1171371..1172246 (+) 876 WP_033900473.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  HUG14_RS05785 (HUG14_05785) - 1172323..1172514 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54695.14 Da        Isoelectric Point: 4.5889

>NTDB_id=415344 HUG14_RS05750 WP_010905315.1 1166276..1167718(-) (vicK) [Lactococcus lactis strain K_LL005]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=415344 HUG14_RS05750 WP_010905315.1 1166276..1167718(-) (vicK) [Lactococcus lactis strain K_LL005]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGTAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTTTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CIG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442