Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   H8S71_RS09085 Genome accession   NZ_CP060417
Coordinates   1749304..1751184 (+) Length   626 a.a.
NCBI ID   WP_187002294.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain ONU 559     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1744304..1756184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H8S71_RS09070 (H8S71_09065) ymcA 1745341..1745772 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  H8S71_RS09075 (H8S71_09070) cotE 1746034..1746579 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  H8S71_RS09080 (H8S71_09075) hexA 1746712..1749288 (+) 2577 WP_003231832.1 DNA mismatch repair protein MutS Machinery gene
  H8S71_RS09085 (H8S71_09080) hexB 1749304..1751184 (+) 1881 WP_187002294.1 DNA mismatch repair endonuclease MutL Machinery gene
  H8S71_RS09090 (H8S71_09085) ymzD 1751584..1752039 (-) 456 WP_080286208.1 regulatory YrvL family protein -
  H8S71_RS09095 (H8S71_09090) - 1752194..1752745 (-) 552 WP_187002232.1 hypothetical protein -
  H8S71_RS09100 (H8S71_09095) pksA 1752866..1753474 (+) 609 WP_125121341.1 TetR/AcrR family transcriptional regulator -
  H8S71_RS09105 (H8S71_09100) pksB 1753673..1754350 (+) 678 WP_169037513.1 MBL fold metallo-hydrolase -
  H8S71_RS09110 (H8S71_09105) - 1754461..1754727 (+) 267 WP_120363368.1 hypothetical protein -
  H8S71_RS09115 (H8S71_09110) fabD 1754724..1755590 (+) 867 WP_021479264.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 70394.26 Da        Isoelectric Point: 5.6804

>NTDB_id=415050 H8S71_RS09085 WP_187002294.1 1749304..1751184(+) (hexB) [Bacillus subtilis subsp. subtilis strain ONU 559]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTIEVSDVSAEEPETFEQEGHEEQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGE
VEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDIK
KLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=415050 H8S71_RS09085 WP_187002294.1 1749304..1751184(+) (hexB) [Bacillus subtilis subsp. subtilis strain ONU 559]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCGAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGTAAGCGTGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGGAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAATGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTTCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAGGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCATTGAGGTGTCCGATGTTTCAGCAGAAGAGCCTGAAACATTTGAGCAGGAAGGCCATGAGGA
ACAGCAGCCAGCGTCTGAGCGGGTTCCAATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAAACG
AAAACGGCCTATATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGGGAG
GTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACAGCA
CAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGGCCT
GGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATTAAA
AAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGAAAT
CAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACCATT
CCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(441-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.118

100

0.474