Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GNE05_RS16145 Genome accession   NZ_CP047644
Coordinates   3257901..3258545 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus sp. AM1(2019)     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3252901..3263545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GNE05_RS16110 (GNE05_16110) - 3254086..3254517 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  GNE05_RS16115 (GNE05_16115) - 3254517..3254858 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  GNE05_RS16120 (GNE05_16120) - 3254851..3256332 (+) 1482 WP_041482212.1 Na+/H+ antiporter subunit D -
  GNE05_RS16125 (GNE05_16125) - 3256338..3256814 (+) 477 WP_052827786.1 Na+/H+ antiporter subunit E -
  GNE05_RS16130 (GNE05_16130) - 3256814..3257098 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  GNE05_RS16135 (GNE05_16135) mnhG 3257082..3257456 (+) 375 WP_007613429.1 monovalent cation/H(+) antiporter subunit G -
  GNE05_RS16140 (GNE05_16140) - 3257496..3257879 (-) 384 WP_160182981.1 hotdog fold thioesterase -
  GNE05_RS16145 (GNE05_16145) comA 3257901..3258545 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  GNE05_RS16150 (GNE05_16150) comP 3258626..3260977 (-) 2352 WP_328700097.1 histidine kinase Regulator
  GNE05_RS16155 (GNE05_16155) comX 3260955..3261125 (-) 171 WP_032863917.1 competence pheromone ComX -
  GNE05_RS16160 (GNE05_16160) - 3261125..3262051 (-) 927 WP_014721741.1 polyprenyl synthetase family protein -
  GNE05_RS16165 (GNE05_16165) degQ 3262182..3262322 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  GNE05_RS16170 (GNE05_16170) - 3262787..3263128 (+) 342 WP_021495366.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=414896 GNE05_RS16145 WP_003152052.1 3257901..3258545(-) (comA) [Bacillus sp. AM1(2019)]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=414896 GNE05_RS16145 WP_003152052.1 3257901..3258545(-) (comA) [Bacillus sp. AM1(2019)]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment