Detailed information NTG0414732

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GU333_RS03275
• Genome accession: NZ_CP047630
• Coordinates: 656662..658950 (+)
• Length: 762 a.a.
• NCBI ID: WP_167841924.1
• Uniprot ID: -
• Organism: Lactococcus raffinolactis strain Lr_18_12S
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 651662..663950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GU333_RS03265 (GU333_03255)	dnaG	653439..655292 (+)	1854	WP_167841157.1	DNA primase	-
GU333_RS03270 (GU333_03260)	rpoD	655295..656425 (+)	1131	WP_167841923.1	RNA polymerase sigma factor RpoD	-
GU333_RS03275 (GU333_03265)	clpC	656662..658950 (+)	2289	WP_167841924.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GU333_RS03280 (GU333_03270)	def	659039..659659 (-)	621	WP_167841925.1	peptide deformylase	-
GU333_RS03285 (GU333_03275)	uvrB	659731..661719 (+)	1989	WP_167841926.1	excinuclease ABC subunit UvrB	-
GU333_RS03290 (GU333_03280)	-	662199..662486 (+)	288	WP_061775386.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 762 a.a.
• Molecular weight: 84091.87 Da
• Isoelectric Point: 4.7607

>NTDB_id=414732 GU333_RS03275 WP_167841924.1 656662..658950(+) (clpC) [Lactococcus raffinolactis strain Lr_18_12S]
MLCQNCQLNEATIHLYTNVNGVKKQNDLCQNCYQIMKSGGPTNLFGGGANQGATNQSDANYNPFDDLFGTLGNNMNHPNG
RPDNATPPTQTGRGGNGGQPPRGRAGNAQPKGMLEDFGFNVTESARKGEIDPVIGRDQEITRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMKEISERQDVILFIDEIHEIVGAGS
AGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQKRYEDYHHVKYTDE
AIEQAAILSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPQEIAKRIQSSEDAKNEALRSEDFEKAAHFRDQIAKLRE
LSKQELTDEETPVITEKDIESIIEEKTKIPVGDLKEKEQTQLINLADDLKAHVIGQDDAIDKISKAVRRNRVGLGKANRP
IGSFMFVGPTGVGKTELAKQLALELFGSQDSMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTEKVRRNPYSLILLD
EIEKAHPDVMHMFLQILDDGRLTDAQGRTISFKDTIIIMTSNAGTGKVEANVGFGAAREGTTNSVLAQLGDFFSPEFMNR
FDGIIEFKALSKDNLLQIVDLMLADVNAQISRNEIHLDVTQAVKEKLVDLGYDPKMGARPLRRTIQDHIEDAIADFYIEH
PEHKMLTADVIDDQIVIVNHSDDATTDGAIAETTADAGSADA

Nucleotide

• Length: 2289 bp

>NTDB_id=414732 GU333_RS03275 WP_167841924.1 656662..658950(+) (clpC) [Lactococcus raffinolactis strain Lr_18_12S]
ATGCTCTGTCAAAATTGTCAACTTAATGAAGCAACGATTCACCTCTACACAAATGTAAATGGTGTCAAAAAACAAAATGA
TCTCTGCCAAAACTGTTACCAAATCATGAAATCAGGTGGACCTACAAATCTTTTTGGTGGTGGTGCTAACCAAGGCGCAA
CCAATCAATCAGATGCTAACTATAATCCCTTCGATGATCTTTTCGGAACATTAGGTAATAATATGAACCATCCTAATGGC
CGACCAGACAATGCCACACCGCCAACACAGACTGGTCGTGGTGGTAATGGTGGTCAACCACCTCGTGGTCGTGCAGGAAA
CGCACAACCCAAAGGTATGCTAGAAGACTTCGGTTTTAACGTGACTGAAAGTGCCCGTAAAGGTGAAATTGACCCAGTCA
TTGGACGTGATCAGGAAATTACTCGCGTGATTGAAATTCTTAATCGCCGGACTAAAAATAATCCTGTTTTAATTGGCGAA
CCTGGTGTTGGTAAAACTGCTGTCGTTGAAGGCTTAGCCCAAAAAATCGTTGATGGTGATGTGCCACAAAAACTACAAAA
TAAAGAAGTTATTCGACTAGATGTTGTGAGCTTGGTCCAAGGGACCGGGATTCGTGGTCAATTTGAAGAACGCATGCAAA
AATTGATGAAAGAAATCTCTGAACGTCAAGATGTGATTCTTTTCATTGATGAAATCCATGAAATCGTGGGTGCTGGTTCT
GCTGGTGACGGTAATATGGATGCTGGCAACATTTTGAAGCCAGCATTGGCTCGTGGTGAATTGCAGCTGGTCGGTGCAAC
AACGCTAAATGAATATCGGATCATTGAAAAAGATGCTGCGCTTGAACGTCGGATGCAACCAGTTAAAGTTGATGAACCTT
CTGTTGATGAAACGATTACTATTTTACGCGGGATTCAAAAACGTTATGAAGACTACCATCACGTGAAATATACGGATGAA
GCGATTGAACAGGCAGCCATCTTGTCTAACCGTTATATTCAAGATCGTTTCTTGCCTGACAAGGCCATTGACTTGTTAGA
TGAGTCTGGATCTAAGAAAAATCTGACCTTAAAATTCGTTGATCCTCAGGAAATTGCCAAACGGATTCAGTCTTCTGAAG
ATGCCAAAAATGAAGCCTTGCGTTCTGAAGACTTCGAAAAAGCAGCACATTTCCGTGATCAAATCGCCAAATTGCGAGAA
TTATCTAAGCAAGAATTGACGGATGAAGAAACACCAGTCATCACTGAAAAAGACATCGAATCTATCATTGAAGAAAAAAC
GAAGATTCCTGTAGGTGATTTGAAAGAAAAAGAACAAACGCAGTTAATCAATTTAGCCGATGACTTGAAAGCGCATGTCA
TTGGTCAAGATGATGCCATTGATAAAATTTCCAAGGCAGTCCGTCGTAACCGTGTAGGCCTTGGGAAAGCCAATCGCCCA
ATCGGTAGCTTTATGTTTGTCGGACCAACGGGTGTTGGTAAAACAGAACTTGCTAAGCAATTAGCCCTGGAGCTTTTCGG
TAGTCAAGACAGCATGATTCGATTCGATATGAGCGAATACATGGAAAAACACAGTGTGGCGAAGCTGATTGGTGCGCCTC
CTGGTTATGTTGGTTATGAAGAAGCAGGGCAACTGACTGAAAAAGTCCGTCGCAATCCTTATTCATTGATCTTACTGGAC
GAAATCGAAAAAGCCCATCCAGATGTTATGCACATGTTCCTACAAATCTTGGACGACGGTCGTCTGACCGATGCTCAAGG
TCGTACGATTAGCTTTAAGGACACGATTATCATCATGACCTCAAATGCAGGGACTGGTAAAGTAGAAGCCAATGTCGGCT
TCGGTGCAGCTCGTGAAGGCACGACAAACTCTGTCTTAGCTCAACTTGGTGATTTCTTCAGCCCTGAGTTCATGAACCGT
TTTGACGGCATCATTGAATTCAAAGCCTTAAGTAAAGACAATCTCCTGCAAATTGTTGACTTGATGCTGGCTGACGTCAA
TGCACAGATTTCAAGAAATGAAATCCATTTGGATGTAACTCAAGCAGTCAAAGAAAAATTAGTTGATCTTGGTTATGATC
CAAAAATGGGCGCTCGACCACTCCGTCGGACTATCCAAGACCATATCGAAGATGCCATCGCAGATTTTTATATCGAACAT
CCCGAACATAAAATGCTCACAGCAGATGTTATTGACGATCAAATCGTCATTGTCAATCATTCTGATGACGCAACAACGGA
TGGAGCTATAGCAGAAACAACAGCTGATGCAGGCTCAGCTGACGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• AAA lid domain (AAA_lid_9) (294-393)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-720)

• ATPase family associated with various cellular activities (AAA) (AAA) (156-275)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	83.089	98.556	0.819
clpE	Streptococcus mutans UA159	76.078	100	0.764
clpE	Streptococcus pneumoniae Rx1	75.672	97.638	0.739
clpE	Streptococcus pneumoniae D39	75.672	97.638	0.739
clpE	Streptococcus pneumoniae R6	75.672	97.638	0.739
clpE	Streptococcus pneumoniae TIGR4	75.672	97.638	0.739
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	88.32	0.442
clpC	Streptococcus pneumoniae Rx1	48.392	81.627	0.395
clpC	Streptococcus pneumoniae TIGR4	48.392	81.627	0.395
clpC	Streptococcus pneumoniae D39	48.392	81.627	0.395
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.987	81.496	0.391
clpC	Streptococcus thermophilus LMD-9	44.932	86.745	0.39
clpC	Streptococcus thermophilus LMG 18311	44.629	86.745	0.387
clpC	Streptococcus mutans UA159	46.667	80.709	0.377