Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HMPREF0833_RS02925 Genome accession   NC_015678
Coordinates   597612..598844 (-) Length   410 a.a.
NCBI ID   WP_003001797.1    Uniprot ID   V8BGN3
Organism   Streptococcus parasanguinis ATCC 15912     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 592612..603844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS02895 (HMPREF0833_10573) - 593191..593761 (-) 571 Protein_563 iron-containing alcohol dehydrogenase -
  HMPREF0833_RS02900 (HMPREF0833_10574) rplL 594007..594375 (-) 369 WP_003016256.1 50S ribosomal protein L7/L12 -
  HMPREF0833_RS02905 (HMPREF0833_10575) rplJ 594450..594950 (-) 501 WP_003016269.1 50S ribosomal protein L10 -
  HMPREF0833_RS02910 (HMPREF0833_10576) - 595185..595982 (-) 798 WP_003016373.1 formate/nitrite transporter family protein -
  HMPREF0833_RS02915 (HMPREF0833_10577) - 596147..596848 (-) 702 WP_013903635.1 glucosaminidase domain-containing protein -
  HMPREF0833_RS02920 (HMPREF0833_10578) yihA 596998..597600 (-) 603 WP_013903636.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HMPREF0833_RS02925 (HMPREF0833_10579) clpX 597612..598844 (-) 1233 WP_003001797.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HMPREF0833_RS02935 (HMPREF0833_10581) - 599053..599562 (-) 510 WP_013903637.1 dihydrofolate reductase -
  HMPREF0833_RS02940 (HMPREF0833_10582) - 599770..600609 (-) 840 WP_013903638.1 thymidylate synthase -
  HMPREF0833_RS02945 (HMPREF0833_10583) - 600703..601662 (-) 960 WP_003016364.1 ROK family glucokinase -
  HMPREF0833_RS02950 (HMPREF0833_10584) - 601748..602266 (-) 519 WP_013903639.1 DUF308 domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45663.16 Da        Isoelectric Point: 4.3940

>NTDB_id=41375 HMPREF0833_RS02925 WP_003001797.1 597612..598844(-) (clpX) [Streptococcus parasanguinis ATCC 15912]
MPTNQNNDMMVYCSFCGKSQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREDETDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGKNNKAIDESSSYMQEIVAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDNVELEFDDEALQEIANKAIERKTGARGLRSIIEETMMDVMFEIPSQEDVKLVRITKEAVD
GTEKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=41375 HMPREF0833_RS02925 WP_003001797.1 597612..598844(-) (clpX) [Streptococcus parasanguinis ATCC 15912]
ATGCCAACGAATCAAAATAATGATATGATGGTTTATTGTTCATTTTGCGGAAAGAGTCAAGATGAAGTCCAAAAAATCAT
TGCAGGGAACAATGCGTTTATCTGTAATGAATGTGTAGAGTTAGCACAAGAAATTATTCGTGAGGAGCTAGCAGAAGAAG
TTCTTGCAGACCTTAGTGAAGTTCCAAAACCAATCGAATTGCTCAATATCTTGAACCACTATGTGATCGGTCAAGATCGT
GCCAAACGTGCCCTTGCTGTAGCAGTATACAACCACTACAAACGCATTAACTTCCACGATACGCGCGAAGATGAGACAGA
TGTTGAATTACAAAAATCAAACATCCTCATGATTGGACCGACTGGTTCAGGTAAGACTTTCTTGGCCCAGACCTTAGCAC
GTAGCTTGAATGTCCCATTTGCTATTGCCGATGCAACAGCCTTGACAGAAGCTGGTTATGTGGGAGAAGACGTTGAAAAC
ATTCTCTTGAAACTTCTTCAAGCAGCTGATTTCAACATCGAGCGTGCAGAACGAGGCATTATCTACGTCGATGAAATTGA
TAAGATTGCTAAGAAAAGTGAAAATGTCTCTATCACACGTGACGTTTCTGGTGAAGGGGTGCAACAAGCCCTCTTGAAGA
TCATCGAAGGAACCGTCGCTAGTGTCCCACCTCAAGGTGGACGCAAACACCCGCAACAAGAGATGATCCAAGTGGATACC
AAGAACATCCTCTTTATCGTAGGTGGAGCTTTTGACGGGATCGAAGAAATTGTTAAACAACGTCTTGGTGAAAAAGTCAT
CGGTTTCGGTAAGAACAATAAAGCTATTGATGAATCAAGCTCTTACATGCAAGAAATCGTTGCAGAAGATATTCAAAAAT
TCGGGATTATCCCAGAATTGATCGGACGTCTTCCAGTCTTTGCAGCTCTTGAGCAATTGACAGTTGACGATCTTGTCCGT
ATTCTAAAAGAGCCACGCAATGCCTTGGTAAAACAATACCAAACCTTGCTCTCTTATGATAACGTTGAATTGGAATTCGA
TGATGAAGCTCTTCAAGAAATTGCTAATAAGGCCATCGAAAGAAAAACAGGAGCTCGTGGACTTCGTTCGATTATCGAAG
AAACGATGATGGATGTCATGTTTGAAATTCCAAGTCAAGAAGATGTCAAACTTGTCCGAATCACAAAAGAAGCTGTAGAT
GGAACTGAAAAACCAATTCTTGAAACAGCCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB V8BGN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.711

98.049

0.566

Multiple sequence alignment