Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H4P46_RS09985 Genome accession   NZ_CP060083
Coordinates   2079059..2079715 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain G1/2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2074059..2084715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4P46_RS09955 (H4P46_09955) dcyD 2074938..2075924 (+) 987 WP_001695857.1 D-cysteine desulfhydrase -
  H4P46_RS09960 (H4P46_09960) tcyL 2075939..2076607 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H4P46_RS09965 (H4P46_09965) tcyN 2076604..2077356 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H4P46_RS09970 (H4P46_09970) sdiA 2077586..2078308 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  H4P46_RS09975 (H4P46_09975) yecF 2078376..2078600 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H4P46_RS09980 (H4P46_09980) yecU 2078587..2078763 (-) 177 WP_001302050.1 protein YecU -
  H4P46_RS26745 - 2078801..2078917 (-) 117 WP_001302039.1 hypothetical protein -
  H4P46_RS09985 (H4P46_09985) letA 2079059..2079715 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H4P46_RS09990 (H4P46_09990) uvrC 2079712..2081544 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  H4P46_RS09995 (H4P46_09995) pgsA 2081601..2082149 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H4P46_RS10015 (H4P46_10015) - 2082845..2083585 (-) 741 WP_022581686.1 hypothetical protein -
  H4P46_RS26750 (H4P46_10020) - 2083666..2084142 (+) 477 Protein_1988 Arm DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=413227 H4P46_RS09985 WP_000611328.1 2079059..2079715(+) (letA) [Escherichia coli strain G1/2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=413227 H4P46_RS09985 WP_000611328.1 2079059..2079715(+) (letA) [Escherichia coli strain G1/2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482