Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H4P48_RS08750 Genome accession   NZ_CP060073
Coordinates   1856506..1857162 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain G4/9     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1851506..1862162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4P48_RS08720 (H4P48_08720) dcyD 1852385..1853371 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  H4P48_RS08725 (H4P48_08725) tcyL 1853386..1854054 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H4P48_RS08730 (H4P48_08730) tcyN 1854051..1854803 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H4P48_RS08735 (H4P48_08735) sdiA 1855033..1855755 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  H4P48_RS08740 (H4P48_08740) yecF 1855823..1856047 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H4P48_RS08745 (H4P48_08745) yecU 1856034..1856210 (-) 177 WP_000590347.1 protein YecU -
  H4P48_RS08750 (H4P48_08750) letA 1856506..1857162 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H4P48_RS08755 (H4P48_08755) uvrC 1857159..1858991 (+) 1833 WP_021570825.1 excinuclease ABC subunit UvrC Machinery gene
  H4P48_RS08760 (H4P48_08760) pgsA 1859048..1859596 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H4P48_RS08780 (H4P48_08780) - 1860291..1861031 (-) 741 Protein_1745 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=413058 H4P48_RS08750 WP_000611328.1 1856506..1857162(+) (letA) [Escherichia coli strain G4/9]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=413058 H4P48_RS08750 WP_000611328.1 1856506..1857162(+) (letA) [Escherichia coli strain G4/9]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
ACCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482