Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   H4990_RS03890 Genome accession   NZ_CP059969
Coordinates   748078..748743 (+) Length   221 a.a.
NCBI ID   WP_002884392.1    Uniprot ID   -
Organism   Campylobacter jejuni strain C109     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 743078..753743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4990_RS03860 (H4990_03860) htrA 743402..744820 (+) 1419 WP_002860448.1 serine protease HtrA -
  H4990_RS03865 (H4990_03865) - 744896..745570 (+) 675 WP_002853196.1 response regulator transcription factor -
  H4990_RS03870 (H4990_03870) - 745567..746814 (+) 1248 WP_002853241.1 ArsS family sensor histidine kinase -
  H4990_RS03880 (H4990_03880) - 747072..747320 (-) 249 WP_002859295.1 ribbon-helix-helix domain-containing protein -
  H4990_RS03885 (H4990_03885) - 747331..747930 (-) 600 WP_002859294.1 bacteriohemerythrin -
  H4990_RS03890 (H4990_03890) ciaR 748078..748743 (+) 666 WP_002884392.1 two-component system response regulator DccR Regulator
  H4990_RS03895 (H4990_03895) dccS 748736..749616 (+) 881 Protein_754 two-component system sensor histidine kinase DccS -
  H4990_RS03900 (H4990_03900) rny 749617..750972 (+) 1356 Protein_755 ribonuclease Y -
  H4990_RS03905 (H4990_03905) - 750981..751538 (+) 558 WP_002852823.1 DedA family protein -
  H4990_RS03910 (H4990_03910) - 751538..752797 (+) 1260 WP_002867371.1 ComEC/Rec2 family competence protein -
  H4990_RS03915 (H4990_03915) rbn 752741..753547 (-) 807 WP_002852725.1 YihY/virulence factor BrkB family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25569.28 Da        Isoelectric Point: 4.6834

>NTDB_id=412001 H4990_RS03890 WP_002884392.1 748078..748743(+) (ciaR) [Campylobacter jejuni strain C109]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGLRFEFTTQILYHNNKALALPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=412001 H4990_RS03890 WP_002884392.1 748078..748743(+) (ciaR) [Campylobacter jejuni strain C109]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGGG
ATGGACTTAGGTTCGAATTTACTACACAAATTCTTTATCATAATAATAAAGCTTTGGCTTTGCCGAGTAAAGAGATTAAA
CTTTTGTCTTTATTGCTTAAAAATAAAAACAACTTTTTAAGCACAGAGAGAATTTTTGAAGAACTTTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGAGCTTATGTAAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAACCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362

Multiple sequence alignment