NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	H4992_RS06930	Genome accession	NZ_CP059967
Coordinates	1291883..1292548 (-)	Length	221 a.a.
NCBI ID	WP_002853205.1	Uniprot ID	Q0P933
Organism	Campylobacter jejuni strain C201
Function	repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1286883..1297548

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H4992_RS06905 (H4992_06905)	flgS	1287114..1288133 (-)	1020	WP_002868504.1	fla regulon two-component system sensor histidine kinase FlgS	-
H4992_RS06910 (H4992_06910)	-	1288137..1289015 (-)	879	WP_002852402.1	DUF234 domain-containing protein	-
H4992_RS06915 (H4992_06915)	-	1289051..1290325 (+)	1275	WP_079254748.1	aminotransferase class V-fold PLP-dependent enzyme	-
H4992_RS06920 (H4992_06920)	purU	1290322..1291020 (-)	699	Protein_1360	formyltetrahydrofolate deformylase	-
H4992_RS06925 (H4992_06925)	dccS	1291045..1291890 (-)	846	Protein_1361	two-component system sensor histidine kinase DccS	-
H4992_RS06930 (H4992_06930)	ciaR	1291883..1292548 (-)	666	WP_002853205.1	two-component system response regulator DccR	Regulator
H4992_RS06935 (H4992_06935)	-	1292696..1293295 (+)	600	WP_002859294.1	bacteriohemerythrin	-
H4992_RS06940 (H4992_06940)	-	1293306..1293554 (+)	249	WP_002853192.1	ribbon-helix-helix domain-containing protein	-
H4992_RS06950 (H4992_06950)	-	1293812..1295059 (-)	1248	WP_002868562.1	ArsS family sensor histidine kinase	-
H4992_RS06955 (H4992_06955)	-	1295056..1295730 (-)	675	WP_002853196.1	response regulator transcription factor	-
H4992_RS06960 (H4992_06960)	htrA	1295806..1297224 (-)	1419	WP_002868561.1	serine protease HtrA	-

Sequence

Protein

Download Length: 221 a.a. Molecular weight: 25633.32 Da Isoelectric Point: 4.6834

                                >NTDB_id=411919 H4992_RS06930 WP_002853205.1 1291883..1292548(-) (ciaR) [Campylobacter jejuni strain C201]

MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM

TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK

LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide

Download Length: 666 bp

                                >NTDB_id=411919 H4992_RS06930 WP_002853205.1 1291883..1292548(-) (ciaR) [Campylobacter jejuni strain C201]

ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA

TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG

TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG

ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT

TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG

ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG

CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGTACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA

GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA

GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus pneumoniae Rx1	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae D39	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae R6	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae TIGR4	36.364	99.548	0.362

Detailed information NTG0411919