Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GRI05_RS08035 Genome accession   NZ_CP047248
Coordinates   1622163..1622852 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain LSM178     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1617163..1627852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GRI05_RS08010 (GRI05_08190) - 1617634..1618259 (-) 626 Protein_1541 nitroreductase family protein -
  GRI05_RS08015 (GRI05_08200) dnaI 1618343..1619242 (-) 900 WP_012027642.1 primosomal protein DnaI -
  GRI05_RS08020 (GRI05_08205) - 1619242..1620393 (-) 1152 WP_012027643.1 replication initiation/membrane attachment protein -
  GRI05_RS08025 (GRI05_08210) nrdR 1620380..1620871 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  GRI05_RS08030 (GRI05_08215) - 1620943..1622073 (-) 1131 WP_012027644.1 AI-2E family transporter -
  GRI05_RS08035 (GRI05_08220) covR 1622163..1622852 (-) 690 WP_012027645.1 response regulator transcription factor Regulator
  GRI05_RS08040 (GRI05_08225) gndA 1622934..1624361 (-) 1428 WP_012028448.1 NADP-dependent phosphogluconate dehydrogenase -
  GRI05_RS08045 (GRI05_08230) - 1624458..1624997 (-) 540 WP_012027649.1 YceD family protein -
  GRI05_RS08050 (GRI05_08235) trxB 1625007..1625924 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  GRI05_RS08055 (GRI05_08240) - 1625938..1626162 (-) 225 WP_002936682.1 DUF4059 family protein -
  GRI05_RS08060 (GRI05_08245) - 1626180..1627523 (-) 1344 WP_012027650.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=411870 GRI05_RS08035 WP_012027645.1 1622163..1622852(-) (covR) [Streptococcus suis strain LSM178]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=411870 GRI05_RS08035 WP_012027645.1 1622163..1622852(-) (covR) [Streptococcus suis strain LSM178]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAAAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTGGTGAAGCCCTTTGTCAT
TAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGCTGGCAACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment