Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H5C78_RS13575 Genome accession   NZ_CP059917
Coordinates   2789586..2790242 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 64.1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2784586..2795242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H5C78_RS13545 (H5C78_13545) yecA 2785837..2786502 (-) 666 WP_182917214.1 UPF0149 family protein YecA -
  H5C78_RS13565 (H5C78_13565) pgsA 2787152..2787700 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H5C78_RS13570 (H5C78_13570) uvrC 2787757..2789589 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  H5C78_RS13575 (H5C78_13575) letA 2789586..2790242 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H5C78_RS27405 - 2790384..2790455 (+) 72 Protein_2700 transcriptional regulator -
  H5C78_RS13580 (H5C78_13580) yecU 2790538..2790714 (+) 177 WP_000590347.1 protein YecU -
  H5C78_RS13585 (H5C78_13585) yecF 2790701..2790925 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  H5C78_RS13590 (H5C78_13590) sdiA 2790993..2791715 (-) 723 WP_001154268.1 transcriptional regulator SdiA -
  H5C78_RS13595 (H5C78_13595) tcyN 2791945..2792697 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H5C78_RS13600 (H5C78_13600) tcyL 2792694..2793362 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  H5C78_RS13605 (H5C78_13605) dcyD 2793377..2794363 (-) 987 WP_001128205.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=411541 H5C78_RS13575 WP_000611335.1 2789586..2790242(-) (letA) [Escherichia coli strain 64.1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=411541 H5C78_RS13575 WP_000611335.1 2789586..2790242(-) (letA) [Escherichia coli strain 64.1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment