Detailed information NTG0410745

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GQ677_RS06990
• Genome accession: NZ_CP047120
• Coordinates: 1354355..1355584 (-)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1085
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1349355..1360584

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQ677_RS06970 (GQ677_06970)	rpiA	1349814..1350497 (-)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-
GQ677_RS06975 (GQ677_06975)	-	1350879..1352796 (+)	1918	Protein_1312	AAA family ATPase	-
GQ677_RS06980 (GQ677_06980)	-	1352855..1353598 (-)	744	WP_002984942.1	hypothetical protein	-
GQ677_RS06985 (GQ677_06985)	yihA	1353746..1354345 (-)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
GQ677_RS06990 (GQ677_06990)	clpX	1354355..1355584 (-)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
GQ677_RS06995 (GQ677_06995)	-	1355714..1355884 (-)	171	WP_002990165.1	hypothetical protein	-
GQ677_RS07000 (GQ677_07000)	-	1355904..1356401 (-)	498	WP_002984955.1	dihydrofolate reductase	-
GQ677_RS07005 (GQ677_07005)	-	1356481..1357320 (-)	840	WP_002990167.1	thymidylate synthase	-
GQ677_RS07010 (GQ677_07010)	-	1357529..1358704 (+)	1176	WP_010922171.1	hydroxymethylglutaryl-CoA synthase	-
GQ677_RS07015 (GQ677_07015)	-	1358691..1359968 (+)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=410745 GQ677_RS06990 WP_009880296.1 1354355..1355584(-) (clpX) [Streptococcus pyogenes strain 1085]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=410745 GQ677_RS06990 WP_009880296.1 1354355..1355584(-) (clpX) [Streptococcus pyogenes strain 1085]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575