Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   GQX63_RS02575 Genome accession   NZ_CP047021
Coordinates   553255..553824 (+) Length   189 a.a.
NCBI ID   WP_045176736.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M2024     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 548255..558824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQX63_RS02550 (GQX63_02560) cysE 549468..550115 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  GQX63_RS02555 (GQX63_02565) cysS 550099..551499 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  GQX63_RS02560 (GQX63_02570) - 551492..551896 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  GQX63_RS02565 (GQX63_02575) rlmB 551904..552650 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  GQX63_RS02570 (GQX63_02580) - 552650..553174 (+) 525 WP_000664738.1 NYN domain-containing protein -
  GQX63_RS02575 (GQX63_02585) sigH 553255..553824 (+) 570 WP_045176736.1 RNA polymerase sigma factor Regulator
  GQX63_RS02580 (GQX63_02590) rpmG 553939..554082 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  GQX63_RS02585 (GQX63_02595) secE 554138..554320 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  GQX63_RS02590 (GQX63_02600) nusG 554333..554881 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  GQX63_RS02595 (GQX63_02605) rplK 555062..555484 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  GQX63_RS02600 (GQX63_02610) rplA 555692..556384 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  GQX63_RS02605 (GQX63_02620) rplJ 556656..557156 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  GQX63_RS02610 (GQX63_02625) rplL 557199..557567 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  GQX63_RS02615 (GQX63_02630) - 557742..558350 (+) 609 WP_023913388.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23113.96 Da        Isoelectric Point: 9.5790

>NTDB_id=409881 GQX63_RS02575 WP_045176736.1 553255..553824(+) (sigH) [Staphylococcus aureus strain M2024]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQYKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=409881 GQX63_RS02575 WP_045176736.1 553255..553824(+) (sigH) [Staphylococcus aureus strain M2024]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTATAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment