Detailed information NTG0409457

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GPZ88_RS09650
• Genome accession: NZ_CP046919
• Coordinates: 1907814..1909043 (-)
• Length: 409 a.a.
• NCBI ID: WP_166044285.1
• Uniprot ID: A0A6G8I2M9
• Organism: Streptococcus ruminicola strain CNU_G2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1902814..1914043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPZ88_RS09630 (GPZ88_09605)	-	1904041..1904709 (+)	669	WP_074561098.1	YoaK family protein	-
GPZ88_RS09635 (GPZ88_09610)	mmuM	1904742..1905686 (-)	945	WP_166044281.1	homocysteine S-methyltransferase	-
GPZ88_RS09640 (GPZ88_09615)	-	1905697..1907073 (-)	1377	WP_166044283.1	amino acid permease	-
GPZ88_RS09645 (GPZ88_09620)	yihA	1907210..1907803 (-)	594	WP_074560304.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
GPZ88_RS09650 (GPZ88_09625)	clpX	1907814..1909043 (-)	1230	WP_166044285.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
GPZ88_RS09655 (GPZ88_09635)	-	1909272..1909766 (-)	495	WP_166044287.1	dihydrofolate reductase	-
GPZ88_RS09660 (GPZ88_09640)	-	1909849..1910688 (-)	840	WP_039696780.1	thymidylate synthase	-
GPZ88_RS09665 (GPZ88_09645)	-	1911019..1912194 (+)	1176	WP_039696779.1	hydroxymethylglutaryl-CoA synthase	-
GPZ88_RS09670 (GPZ88_09650)	-	1912184..1913455 (+)	1272	WP_157629096.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45227.75 Da
• Isoelectric Point: 4.4880

>NTDB_id=409457 GPZ88_RS09650 WP_166044285.1 1907814..1909043(-) (clpX) [Streptococcus ruminicola strain CNU_G2]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQSNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSREEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=409457 GPZ88_RS09650 WP_166044285.1 1907814..1909043(-) (clpX) [Streptococcus ruminicola strain CNU_G2]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAGATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATATAACCACTACAAACGTGTTTCTTTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTACAAAAATCTAACATCCTATTAATCGGACCAACTGGTTCAGGGAAAACATTCCTTGCCCAAACTTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGACGCGACATCATTGACAGAAGCAGGATATGTTGGTGAGGACGTTGAAAACATC
CTTTTGAAACTTATTCAAGCGGCTGATTTTAATATTGAACGTGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGCGAAAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTCCAACAAGCTCTCCTTAAAATCA
TTGAAGGAACAGTAGCAAGCGTTCCACCACAAGGTGGTCGTAAACACCCTAACCAAGAAATGATTCAAATCAATACTAAG
AACATTCTTTTCATCGTTGGTGGTGCTTTTGATGGTATCGAAGACATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAGCAACCGCAAGATTGATGAAGATGCTTCTTACATGCAAGAAATCATCTCCGAAGATATTCAAAAATTTG
GTTTGATTCCTGAATTTATCGGGCGCTTGCCAGTCGTTGCTGCGCTTGAACAATTGACAACAGATGATTTGGTGCGAATC
TTGACAGAACCTCGTAATGCTTTGGTTAAACAATACCAAACACTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGACGCCCTTCAAGCTATTGCTAATAAGGCTATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGAAGAAGTCACTAAAGTCCGTATCACAAAAGATGCTGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

3D structure

• AlphaFold DB: A0A6G8I2M9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577