Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GPZ88_RS06715 Genome accession   NZ_CP046919
Coordinates   1300620..1301918 (+) Length   432 a.a.
NCBI ID   WP_166043784.1    Uniprot ID   A0A6G8I0Q8
Organism   Streptococcus ruminicola strain CNU_G2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1295620..1306918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS06690 (GPZ88_06670) - 1296285..1296929 (+) 645 WP_039695886.1 response regulator transcription factor -
  GPZ88_RS06695 (GPZ88_06675) - 1297054..1298454 (+) 1401 WP_081348706.1 Cof-type HAD-IIB family hydrolase -
  GPZ88_RS06700 (GPZ88_06680) - 1298454..1298810 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  GPZ88_RS06705 (GPZ88_06685) cysK 1298910..1299839 (-) 930 WP_074626743.1 cysteine synthase A -
  GPZ88_RS06710 (GPZ88_06690) - 1299939..1300565 (-) 627 WP_166043782.1 YigZ family protein -
  GPZ88_RS06715 (GPZ88_06695) comFA/cflA 1300620..1301918 (+) 1299 WP_166043784.1 DEAD/DEAH box helicase Machinery gene
  GPZ88_RS06720 (GPZ88_06700) - 1301918..1302580 (+) 663 WP_166043786.1 ComF family protein -
  GPZ88_RS06725 (GPZ88_06705) hpf 1302657..1303205 (+) 549 WP_039695883.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49172.46 Da        Isoelectric Point: 9.8339

>NTDB_id=409445 GPZ88_RS06715 WP_166043784.1 1300620..1301918(+) (comFA/cflA) [Streptococcus ruminicola strain CNU_G2]
MTELNDYYGRIFTESQLTDDLKKEAKVLPSIKREKGQMICNRCGSVMEANQMLQTGRIYCRECLVFGRNTSDSNLYYFPQ
KPFTKTQSLNWQGKLTPYQDEVSKGMLKGITEKQDLLIHAVTGAGKTEMIYQSLAKVIDNGGSVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSEPYKRSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYHAVNQSLKDDGVKLFLTATST
DELDKKVKKGELTKLHLARRFHANPLVVPKMVWLSKVLISMKKKKFPPKLISLLKKQRQSQFPLLIFFPNIEQGREFTSI
LQSIFLDERIGFVSSKTENRLELVEEFRQGKLTILVTTTILERGVTFPCVDVFVLLANHKLYSKSALVQISGRVGRAAER
PTGELLFLHDGVTKAMKKAISEIKEMNHKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=409445 GPZ88_RS06715 WP_166043784.1 1300620..1301918(+) (comFA/cflA) [Streptococcus ruminicola strain CNU_G2]
ATGACAGAGTTAAATGATTACTATGGAAGAATTTTTACAGAAAGTCAGTTAACAGATGACTTGAAAAAAGAAGCAAAAGT
CCTTCCTTCGATTAAAAGAGAAAAAGGGCAAATGATTTGCAATCGCTGTGGAAGTGTAATGGAAGCAAATCAAATGTTGC
AAACTGGTCGCATTTATTGTAGAGAGTGTTTAGTTTTTGGGCGAAATACTAGTGATTCTAATCTTTATTATTTCCCTCAG
AAGCCTTTTACAAAGACTCAGTCTTTAAATTGGCAAGGAAAACTAACTCCTTATCAAGATGAAGTTTCTAAAGGCATGCT
TAAAGGTATTACAGAAAAACAAGATTTATTGATTCACGCCGTGACTGGTGCTGGTAAAACTGAAATGATTTATCAATCTT
TAGCTAAAGTTATTGATAATGGTGGAAGTGTCTGCTTAGCGAGTCCACGGATTGATGTTTGTTTAGAACTTTATAAACGT
TTATCACGGGATTTTTCTTGCCCGATTACGCTTTTACACGGTGATTCTGAGCCGTATAAACGTTCTCCACTGGTAATTGC
AACGACCCATCAACTTTTAAAATTTTACCGAGCATTTGATTTATTAATCATCGACGAAGTTGATGCCTTTCCCTTTGTTG
ACAATAAAATGCTTTATCACGCTGTCAATCAATCGCTAAAAGATGATGGCGTTAAACTCTTTTTAACAGCGACTTCGACT
GATGAACTTGATAAAAAGGTGAAAAAAGGAGAGTTGACAAAGCTGCATTTGGCAAGACGTTTTCATGCCAATCCTTTGGT
AGTCCCCAAAATGGTTTGGTTAAGCAAAGTGCTAATTTCAATGAAAAAGAAAAAATTTCCTCCTAAACTAATCTCTCTTT
TAAAAAAACAAAGGCAAAGTCAATTTCCGCTTCTTATCTTTTTTCCGAATATTGAACAAGGTAGAGAATTTACAAGTATC
TTACAAAGCATTTTTCTAGATGAAAGGATAGGATTTGTATCAAGTAAAACTGAAAATCGTTTGGAATTGGTAGAAGAATT
TAGACAAGGAAAATTAACCATACTAGTGACGACAACCATTCTAGAACGTGGGGTAACCTTTCCTTGTGTTGATGTTTTTG
TCCTACTTGCAAATCATAAATTGTACAGCAAAAGTGCACTTGTACAGATATCAGGACGAGTTGGACGAGCAGCCGAGAGA
CCGACAGGAGAGTTATTGTTCTTGCATGATGGCGTAACAAAAGCTATGAAAAAAGCTATTTCTGAAATAAAAGAAATGAA
TCATAAAGGAGGATTTTAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(96-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8I0Q8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

60.656

98.843

0.6
  comFA/cflA Streptococcus pneumoniae D39

60.656

98.843

0.6
  comFA/cflA Streptococcus pneumoniae R6

60.656

98.843

0.6
  comFA/cflA Streptococcus pneumoniae TIGR4

60.656

98.843

0.6
  comFA/cflA Streptococcus mitis NCTC 12261

60.422

98.843

0.597
  comFA/cflA Streptococcus mitis SK321

59.953

98.843

0.593
  comFA Lactococcus lactis subsp. cremoris KW2

49.528

98.148

0.486
  comFA Latilactobacillus sakei subsp. sakei 23K

38.073

100

0.384

Multiple sequence alignment