Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GP482_RS08050 Genome accession   NZ_CP046875
Coordinates   1653547..1654803 (+) Length   418 a.a.
NCBI ID   WP_158914651.1    Uniprot ID   A0A6G8HZL7
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1648547..1659803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS08025 (GP482_08025) - 1649458..1652034 (+) 2577 WP_158914649.1 YfhO family protein -
  GP482_RS08045 (GP482_08045) rlmH 1652852..1653331 (-) 480 WP_039696083.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GP482_RS08050 (GP482_08050) htrA 1653547..1654803 (+) 1257 WP_158914651.1 trypsin-like peptidase domain-containing protein Regulator
  GP482_RS08055 (GP482_08055) spo0J 1654870..1655652 (+) 783 WP_158914653.1 ParB/RepB/Spo0J family partition protein Regulator
  GP482_RS08060 (GP482_08060) dnaA 1655856..1657211 (+) 1356 WP_039696081.1 chromosomal replication initiator protein DnaA -
  GP482_RS08065 (GP482_08065) dnaN 1657370..1658506 (+) 1137 WP_158914655.1 DNA polymerase III subunit beta -
  GP482_RS08070 (GP482_08070) - 1658637..1659521 (+) 885 WP_158914657.1 diacylglycerol kinase family protein -
  GP482_RS08075 (GP482_08075) - 1659532..1659723 (+) 192 WP_039696077.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 43360.56 Da        Isoelectric Point: 4.7392

>NTDB_id=409140 GP482_RS08050 WP_158914651.1 1653547..1654803(+) (htrA) [Streptococcus ruminicola strain CNU_77-61]
MKKIKFRKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSGSSAKTTTSKVSYSNTNDTTKAVEKVGEAVVSV
INYQSNSSSNDLYMQMFGGNLDNNTNNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGE
LVGADTYSDIAVVKIASDKVTTVAEFADSDKITVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGETISTNAI
QTDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLS
DLSTTTISRLNIPTSVTAGIVVASVQSGMPAEGALKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKT
ETIKLTKTTQDLSSSSNQ

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=409140 GP482_RS08050 WP_158914651.1 1653547..1654803(+) (htrA) [Streptococcus ruminicola strain CNU_77-61]
GTGAAAAAAATAAAATTTCGAAAAGTCAATTACAAAAAAATCCTTAAACCACTCTCAGTTATTTTAGTGGGATTCATTGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTGGTTCAAGTGCAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACGAAAGCTGTCGAAAAAGTGGGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAAATGATTTGTATATGCAAATGTTTGGAGGCAATTTAGACAATAACACTAATAA
TAATGGATCAGATAGTGATTTAAGCATCGCTAGTGAAGGTTCAGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTACG
TCGTTACTAATAACCACGTTGTCGATGGTGCTAGCCAAATCGAAATCATGCTTTCTGACGGTACAAAAGTAGTCGGTGAA
TTAGTCGGTGCCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGC
TGATTCAGATAAAATTACTGTTGGTGAAACAGCCATTGCTATTGGTAGCCCTCTAGGTACTGATTACGCTAACTCAGTAA
CCCAAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGAAACAATTTCAACTAATGCTATC
CAAACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTGATCGGTATTAATTC
AAGTAAAATTTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATG
TGGTTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATCCGTCCAGCACTTGGCATCACAATGGCTAACCTAAGC
GATTTATCAACAACAACAATCAGTCGCCTAAATATTCCAACTAGCGTCACAGCTGGTATCGTCGTTGCTTCAGTTCAATC
AGGTATGCCTGCTGAAGGAGCACTTAAAAAATACGATGTCATCACAGCTATCGATGATAAAGATGTTTCTTCTATCACAG
ATCTTCAAAGTGTCCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGATAAGAAAACA
GAAACTATTAAACTAACGAAAACAACACAAGACCTCTCTTCATCATCAAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(120-265)

Peptidase family M50 (Peptidase_M50)

(78-411)

PDZ domain (PDZ_2)

(310-405)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HZL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.179

96.172

0.617
  htrA Streptococcus gordonii str. Challis substr. CH1

60.494

96.89

0.586
  htrA Streptococcus mitis NCTC 12261

58.981

98.565

0.581
  htrA Streptococcus pneumoniae TIGR4

58.738

98.565

0.579
  htrA Streptococcus pneumoniae D39

58.738

98.565

0.579
  htrA Streptococcus pneumoniae Rx1

58.738

98.565

0.579
  htrA Streptococcus pneumoniae R6

58.738

98.565

0.579

Multiple sequence alignment