Detailed information NTG0409111

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GP482_RS04040
• Genome accession: NZ_CP046875
• Coordinates: 820095..821324 (-)
• Length: 409 a.a.
• NCBI ID: WP_074560306.1
• Uniprot ID: A0A1H0YH95
• Organism: Streptococcus ruminicola strain CNU_77-61
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 815095..826324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GP482_RS04020 (GP482_04020)	-	816323..816991 (+)	669	WP_074561098.1	YoaK family protein	-
GP482_RS04025 (GP482_04025)	mmuM	817023..817967 (-)	945	WP_158913995.1	homocysteine S-methyltransferase	-
GP482_RS04030 (GP482_04030)	-	817978..819354 (-)	1377	WP_158913997.1	amino acid permease	-
GP482_RS04035 (GP482_04035)	yihA	819491..820084 (-)	594	WP_074560304.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
GP482_RS04040 (GP482_04040)	clpX	820095..821324 (-)	1230	WP_074560306.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
GP482_RS04050 (GP482_04050)	-	821553..822047 (-)	495	WP_074560308.1	dihydrofolate reductase	-
GP482_RS04055 (GP482_04055)	-	822130..822969 (-)	840	WP_039696780.1	thymidylate synthase	-
GP482_RS04060 (GP482_04060)	-	823298..824473 (+)	1176	WP_074563852.1	hydroxymethylglutaryl-CoA synthase	-
GP482_RS04065 (GP482_04065)	-	824463..825734 (+)	1272	WP_158913999.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45254.78 Da
• Isoelectric Point: 4.4880

>NTDB_id=409111 GP482_RS04040 WP_074560306.1 820095..821324(-) (clpX) [Streptococcus ruminicola strain CNU_77-61]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSREEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=409111 GP482_RS04040 WP_074560306.1 820095..821324(-) (clpX) [Streptococcus ruminicola strain CNU_77-61]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAGATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATATAACCACTACAAACGTGTTTCTTTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTACAAAAATCTAACATCCTATTAATCGGACCAACTGGTTCAGGGAAAACATTCCTTGCCCAAACTTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGACGTTGAAAATATC
CTTTTGAAACTCATTCAAGCAGCTGATTTTAATATTGAACGCGCAGAACGTGGTATCATCTACGTGGATGAAATTGACAA
AATCGCCAAAAAAGGTGAAAATGTCTCAATCACTCGTGATGTTTCAGGTGAAGGTGTTCAACAAGCTCTTCTTAAAATTA
TTGAAGGAACAGTTGCTAGCGTGCCACCACAAGGTGGTCGTAAACACCCTAACCAAGAAATGATTCAAATCAATACTAAG
AATATCCTTTTCATCGTTGGTGGTGCCTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAATAACCGTAAGATTGATGAAGATGCTTCTTATATGCAAGAAATCATCTCCGAAGATATTCAAAAATTTG
GTTTGATTCCTGAATTTATCGGACGCTTGCCAGTCGTTGCTGCGCTTGAACAATTGACAACAGATGATTTGGTGCGAATC
TTGACAGAACCTCGCAATGCTTTGGTTAAACAATACCAAACACTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCTCTTCAAGCTATTGCTAATAAAGCAATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCTATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGAAGAAGTCACTAAAGTCCGTATTACAAAAGATGCCGTCGAAGGC
AAAGACAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A1H0YH95

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577