Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   GPY01_RS10625 Genome accession   NZ_CP046839
Coordinates   1368236..1368847 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 2011EL-1271     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1363236..1373847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPY01_RS10605 - 1363573..1364490 (-) 918 WP_000271072.1 ABC transporter ATP-binding protein -
  GPY01_RS10610 - 1364870..1366516 (-) 1647 WP_000484915.1 SulP family inorganic anion transporter -
  GPY01_RS10615 can 1366664..1367332 (+) 669 WP_001114117.1 carbonate dehydratase -
  GPY01_RS10620 hpt 1367407..1367940 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  GPY01_RS10625 hapR 1368236..1368847 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  GPY01_RS10630 rsmI 1369056..1369922 (-) 867 WP_000131549.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  GPY01_RS10635 - 1369992..1371797 (+) 1806 WP_001015478.1 penicillin-binding protein activator -
  GPY01_RS10640 - 1371829..1372152 (+) 324 WP_000718567.1 YraN family protein -
  GPY01_RS10645 - 1372156..1372746 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  GPY01_RS10650 - 1372749..1373318 (+) 570 WP_000836325.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=408675 GPY01_RS10625 WP_000340100.1 1368236..1368847(+) (hapR) [Vibrio cholerae strain 2011EL-1271]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=408675 GPY01_RS10625 WP_000340100.1 1368236..1368847(+) (hapR) [Vibrio cholerae strain 2011EL-1271]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAACTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTGCAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGCTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment