Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SSU1300283_RS02090 Genome accession   NZ_CP058741
Coordinates   430964..431605 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain 13-00283-02     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 425964..436605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSU1300283_RS02070 (SSU1300283_00418) - 426264..427001 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SSU1300283_RS02075 (SSU1300283_00419) pknB 427001..428659 (+) 1659 Protein_393 Stk1 family PASTA domain-containing Ser/Thr kinase -
  SSU1300283_RS11025 - 428780..428995 (+) 216 Protein_394 serine/threonine protein kinase -
  SSU1300283_RS02080 (SSU1300283_00420) liaF 429320..429979 (+) 660 WP_225585639.1 cell wall-active antibiotics response protein LiaF -
  SSU1300283_RS02085 (SSU1300283_00421) - 429976..430992 (+) 1017 WP_002937028.1 sensor histidine kinase -
  SSU1300283_RS02090 (SSU1300283_00422) vraR 430964..431605 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  SSU1300283_RS02095 (SSU1300283_00423) - 431655..433055 (+) 1401 WP_044667553.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSU1300283_RS02100 (SSU1300283_00424) - 433057..433428 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  SSU1300283_RS02105 (SSU1300283_00425) cysK 433455..434381 (-) 927 WP_002937015.1 cysteine synthase A -
  SSU1300283_RS02110 (SSU1300283_00426) - 434471..435103 (-) 633 WP_004194123.1 YigZ family protein -
  SSU1300283_RS02115 (SSU1300283_00427) comFA/cflA 435182..436465 (+) 1284 WP_014636816.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=407089 SSU1300283_RS02090 WP_002937025.1 430964..431605(+) (vraR) [Streptococcus suis strain 13-00283-02]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=407089 SSU1300283_RS02090 WP_002937025.1 430964..431605(+) (vraR) [Streptococcus suis strain 13-00283-02]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413