Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   GPY00_RS03550 Genome accession   NZ_CP046747
Coordinates   791596..792207 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 3541-04     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 786596..797207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPY00_RS03530 - 786931..787848 (-) 918 WP_033928169.1 ABC transporter ATP-binding protein -
  GPY00_RS03535 - 788229..789875 (-) 1647 WP_032475287.1 SulP family inorganic anion transporter -
  GPY00_RS03540 can 790023..790691 (+) 669 WP_001114117.1 carbonate dehydratase -
  GPY00_RS03545 hpt 790766..791299 (-) 534 WP_000683350.1 hypoxanthine phosphoribosyltransferase -
  GPY00_RS03550 hapR 791596..792207 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  GPY00_RS03555 rsmI 792417..793283 (-) 867 WP_158128453.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  GPY00_RS03560 - 793353..795158 (+) 1806 WP_001015477.1 penicillin-binding protein activator -
  GPY00_RS03565 - 795190..795513 (+) 324 WP_000718567.1 YraN family protein -
  GPY00_RS03570 - 795517..796107 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  GPY00_RS03575 - 796110..796679 (+) 570 WP_019829477.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=407042 GPY00_RS03550 WP_000340100.1 791596..792207(+) (hapR) [Vibrio cholerae strain 3541-04]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=407042 GPY00_RS03550 WP_000340100.1 791596..792207(+) (hapR) [Vibrio cholerae strain 3541-04]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment