Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   GPW70_RS16545 Genome accession   NZ_CP046740
Coordinates   2568832..2569443 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 3566-06     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2563832..2574443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW70_RS16525 - 2564168..2565085 (-) 918 WP_000271068.1 ABC transporter ATP-binding protein -
  GPW70_RS16530 - 2565466..2567112 (-) 1647 WP_000484912.1 SulP family inorganic anion transporter -
  GPW70_RS16535 can 2567260..2567928 (+) 669 WP_001114117.1 carbonate dehydratase -
  GPW70_RS16540 hpt 2568003..2568536 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  GPW70_RS16545 hapR 2568832..2569443 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  GPW70_RS16550 rsmI 2569653..2570519 (-) 867 WP_158106863.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  GPW70_RS16555 - 2570589..2572394 (+) 1806 WP_019829479.1 penicillin-binding protein activator -
  GPW70_RS16560 - 2572381..2572749 (+) 369 WP_019829478.1 YraN family protein -
  GPW70_RS16565 - 2572753..2573343 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  GPW70_RS16570 - 2573346..2573915 (+) 570 WP_019829477.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=406928 GPW70_RS16545 WP_000340100.1 2568832..2569443(+) (hapR) [Vibrio cholerae strain 3566-06]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=406928 GPW70_RS16545 WP_000340100.1 2568832..2569443(+) (hapR) [Vibrio cholerae strain 3566-06]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACCG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTCTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment