Detailed information NTG0406890

Bioinformatically predicted

Overview

• Name: luxQ
• Type: Regulator
• Locus tag: GPW74_RS16040
• Genome accession: NZ_CP046738
• Coordinates: 672554..675127 (+)
• Length: 857 a.a.
• NCBI ID: WP_123011998.1
• Uniprot ID: A0A544JKY1
• Organism: Vibrio cholerae strain 2015V-1126
• Function: autoinducer sensor (predicted from homology) Competence regulation

Genomic Context

Location: 667554..680127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW74_RS16000	-	667602..667853 (-)	252	WP_001882582.1	YgjV family protein	-
GPW74_RS16010	-	668266..668586 (-)	321	WP_001089529.1	DUF496 family protein	-
GPW74_RS16015	-	668774..668971 (+)	198	WP_001246071.1	hypothetical protein	-
GPW74_RS16020	-	669013..669663 (+)	651	WP_123011995.1	YceH family protein	-
GPW74_RS16025	-	669663..669968 (+)	306	WP_123011996.1	GIY-YIG nuclease family protein	-
GPW74_RS16030	traF	670070..671230 (+)	1161	WP_123011997.1	conjugal transfer protein TraF	-
GPW74_RS16035	luxP	671442..672536 (+)	1095	WP_001907859.1	autoinducer 2-binding periplasmic protein LuxP	Regulator
GPW74_RS16040	luxQ	672554..675127 (+)	2574	WP_123011998.1	quorum-sensing autoinducer 2 sensor kinase/phosphatase LuxQ	Regulator
GPW74_RS16045	-	675119..675784 (-)	666	WP_000268197.1	flagellar brake protein	-
GPW74_RS16050	-	676054..677706 (+)	1653	WP_114793961.1	ABC transporter ATP-binding protein	-
GPW74_RS16055	-	677699..679387 (+)	1689	WP_114736299.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 96994.97 Da
• Isoelectric Point: 6.3095

>NTDB_id=406890 GPW74_RS16040 WP_123011998.1 672554..675127(+) (luxQ) [Vibrio cholerae strain 2015V-1126]
MNIRPSQIKHKQRIASFITHAVVVVMGVLIVSVLFQSYQISSRLMAQEGQRTSVQTSSLIQSLFDFRLAALRIHQDSTAK
NISLINALVSRDSSRLDAFFSSVDELELSNAPDLRFISSHDNILWDDGSASFYGIAQQELKKLIRKVAISGNWHLVQTSG
DGKPVHLLMRRSSLIETGTGQVVGYLYVGIVLNDNFALLENIRSGSNSENLVLTVDTTPLVSTLKGSEPYSLDYVVHSGK
DVMRDSFIVGQTFLEVENVPTYLCVYSIQTNQNVLTLRDNFYFWMAFALLSMIGVSIASRWWLQKRIQREIETLMNYTHK
LMELDTKSQFAGSKIYEFDYFGRTLEQSFRRLANKEKQFEDLFNFALSPTMLWNTSGRLIRMNPSAQIQFLREDAQNHFL
FEILERQLLPTITKAAQGNNPSDVTTEVDGRVYRWNLSPIMVEGQIISIITQGQDITTIAEAEKQSQAARREAEESARVR
AEFLAKMSHELRTPLNGVLGVSQLLKRTPLNDEQREHVAVLCSSGEHLLAVLNDILDFSRLEQGKFRIQKNEFRLKELVC
AIDRIYRPLCHEKGLELVVNSNITTATIVRSDQIRINQILFNLLNNAIKFTHQGSIRVELQLIEGDPLAQLVIQVVDTGI
GIREQDLTVIFEPFMQAESTTTREYGGSGLGLTIVHSLVEMLSGQLHVSSEYGIGTRFEIQLPIELVERPDAPQQLLPAP
DPQPLFDKTLRVLLVEDNHTNAFIAQAFCRKYGLDVSWVTDGLQAIEELKIHDYDLVLMDNQLPYLDGVETTRTIKKVLH
LPVVVYACTADGLEETRQAFFHAGAEYVLVKPLKEQTLHKALEHFKYHHGQKNAGLN

Nucleotide

• Length: 2574 bp

>NTDB_id=406890 GPW74_RS16040 WP_123011998.1 672554..675127(+) (luxQ) [Vibrio cholerae strain 2015V-1126]
TTGAACATTCGACCTAGCCAAATCAAGCATAAACAGCGCATCGCTTCATTTATCACCCATGCTGTGGTGGTGGTGATGGG
CGTTCTGATCGTCAGTGTATTATTCCAAAGTTACCAGATCAGTAGCCGCTTGATGGCTCAAGAAGGGCAACGCACCTCAG
TTCAAACCTCCAGCTTGATCCAAAGTTTGTTTGATTTTCGTCTTGCGGCACTGCGAATTCACCAAGACAGCACAGCCAAA
AATATCAGTTTAATCAATGCACTTGTCAGCCGAGATTCGAGTCGGTTGGATGCGTTTTTTTCCAGTGTCGATGAACTTGA
ACTCTCTAATGCACCGGATCTGCGGTTTATTTCCAGTCACGACAACATCCTTTGGGATGATGGCAGCGCCTCCTTTTACG
GCATTGCCCAACAAGAGCTGAAGAAGCTTATCCGTAAAGTGGCGATCAGTGGCAATTGGCATTTGGTTCAAACGTCTGGC
GATGGTAAACCCGTGCATTTGTTAATGCGCCGCTCATCACTGATTGAAACAGGAACTGGGCAGGTGGTTGGGTACCTGTA
TGTGGGAATCGTACTCAATGATAACTTTGCGCTGTTGGAAAATATCCGCAGTGGCAGTAACTCAGAAAACCTAGTTTTGA
CCGTAGACACCACACCGCTGGTCTCCACCTTGAAAGGCAGTGAACCTTATTCGCTGGACTATGTGGTGCACAGTGGAAAA
GATGTCATGAGGGACAGCTTTATTGTTGGCCAAACCTTCTTAGAAGTAGAAAATGTACCGACCTATCTGTGCGTCTACTC
GATTCAGACCAACCAAAATGTGCTCACCCTGCGGGATAATTTCTATTTTTGGATGGCGTTTGCGCTGCTCAGTATGATTG
GTGTTTCCATAGCATCACGCTGGTGGTTACAAAAACGTATTCAGCGAGAAATCGAAACCCTAATGAATTACACCCATAAA
TTGATGGAGCTGGACACCAAGAGCCAGTTTGCTGGTTCTAAAATTTATGAGTTCGACTATTTTGGGCGAACGTTGGAACA
ATCATTCCGTCGTCTCGCCAATAAAGAAAAGCAGTTTGAAGATCTGTTTAACTTTGCGCTCTCACCGACCATGCTTTGGA
ATACCTCTGGTCGACTGATCCGCATGAACCCCTCAGCGCAAATCCAGTTTTTGCGCGAAGATGCGCAAAACCATTTCTTA
TTTGAGATTCTTGAACGCCAACTGTTGCCGACCATCACTAAGGCGGCACAGGGCAATAATCCGAGTGACGTCACAACCGA
AGTGGATGGTCGCGTGTACCGCTGGAACCTTTCACCGATCATGGTGGAAGGGCAGATCATTTCCATCATTACTCAAGGGC
AAGATATCACCACCATCGCGGAAGCGGAGAAACAAAGCCAAGCCGCAAGGCGCGAAGCGGAAGAGTCGGCACGGGTCAGA
GCCGAGTTTTTGGCCAAAATGAGTCACGAATTGCGCACGCCGCTCAATGGTGTGCTCGGCGTTTCCCAACTGCTAAAACG
GACCCCACTCAATGACGAACAGCGCGAACACGTGGCTGTGTTATGCAGCAGTGGTGAACATTTGCTCGCGGTGTTGAATG
ACATCTTGGATTTTTCACGCTTAGAGCAGGGCAAATTCCGTATTCAAAAGAATGAGTTTCGCCTTAAAGAGCTGGTGTGC
GCGATTGACCGCATTTATCGACCTTTATGTCATGAAAAAGGCTTGGAACTGGTGGTGAATTCCAATATCACCACCGCTAC
CATTGTGCGCAGCGATCAGATCCGGATTAACCAAATCTTGTTCAATTTGCTCAATAACGCGATCAAGTTTACTCACCAAG
GTTCGATACGTGTCGAATTGCAATTAATTGAAGGTGATCCGTTAGCTCAGCTGGTGATTCAAGTCGTCGATACGGGGATT
GGTATACGCGAACAAGATTTAACGGTGATTTTTGAACCCTTCATGCAGGCTGAATCGACCACCACTCGAGAGTACGGCGG
AAGTGGTTTAGGCTTAACGATTGTGCACAGTTTAGTGGAAATGCTCAGTGGTCAACTGCACGTCAGCTCCGAGTATGGCA
TCGGTACACGTTTTGAAATTCAGTTACCGATTGAGCTGGTAGAAAGACCGGATGCTCCGCAGCAGTTGTTACCGGCTCCT
GACCCTCAACCGTTATTTGATAAAACTCTGCGTGTACTGTTGGTGGAGGATAACCACACCAACGCCTTTATTGCTCAAGC
ATTCTGTCGTAAGTATGGCTTAGATGTGAGTTGGGTAACCGATGGACTACAGGCGATTGAAGAGCTCAAAATACATGATT
ACGACTTAGTGCTGATGGATAACCAGTTACCCTATCTGGATGGCGTTGAGACCACGCGCACCATCAAAAAGGTGCTGCAT
CTTCCGGTGGTGGTGTATGCCTGTACTGCGGATGGCTTAGAAGAAACACGGCAAGCATTTTTCCATGCGGGCGCGGAATA
TGTATTAGTTAAGCCGCTGAAAGAGCAGACTTTGCATAAAGCGCTGGAGCATTTCAAATATCATCATGGCCAAAAAAACG
CTGGTTTAAATTGA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (480-544)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (592-705)

• Response regulator receiver domain (Response_reg) (732-842)

• LuxQ, periplasmic (LuxQ-periplasm) (41-277)

3D structure

• AlphaFold DB: A0A544JKY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
luxQ	Vibrio cholerae strain A1552	97.083	100	0.971