Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HYQ63_RS10115 Genome accession   NZ_CP058693
Coordinates   2464263..2464919 (-) Length   218 a.a.
NCBI ID   WP_179933513.1    Uniprot ID   -
Organism   Streptomyces sp. Rer75     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2459263..2469919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HYQ63_RS10085 (HYQ63_10085) - 2459869..2460378 (+) 510 WP_179933508.1 HNH endonuclease -
  HYQ63_RS10090 (HYQ63_10090) - 2460450..2461418 (-) 969 WP_123103165.1 SPFH domain-containing protein -
  HYQ63_RS10095 (HYQ63_10095) - 2461556..2461981 (-) 426 WP_179933509.1 NfeD family protein -
  HYQ63_RS10100 (HYQ63_10100) - 2462088..2462879 (-) 792 WP_179933510.1 ABC transporter ATP-binding protein -
  HYQ63_RS10105 (HYQ63_10105) - 2462990..2463793 (+) 804 WP_179933511.1 hypothetical protein -
  HYQ63_RS10110 (HYQ63_10110) - 2463895..2464125 (-) 231 WP_179933512.1 chaplin -
  HYQ63_RS10115 (HYQ63_10115) vraR 2464263..2464919 (-) 657 WP_179933513.1 response regulator transcription factor Regulator
  HYQ63_RS10120 (HYQ63_10120) - 2464912..2466069 (-) 1158 WP_179933514.1 GAF domain-containing sensor histidine kinase -
  HYQ63_RS10125 (HYQ63_10125) - 2466529..2467269 (+) 741 WP_179933515.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23592.86 Da        Isoelectric Point: 5.3998

>NTDB_id=406501 HYQ63_RS10115 WP_179933513.1 2464263..2464919(-) (vraR) [Streptomyces sp. Rer75]
MGERRDGAAIRVLLVDDHQVVRRGLRTFLEVQDDIDVVGEGSDGEEGIARAEELRPDIVLMDVKMPGIDGIEALRKLRDL
DNPARVLVVTSFTEKRTVVPALRAGAAGYVYKDVDPDALASAIRSVHAGHVVLQPEVADALLSQDEVGGGQGRGGSLTDR
EREVLGLIADGRSNREIARRLVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGIGA

Nucleotide


Download         Length: 657 bp        

>NTDB_id=406501 HYQ63_RS10115 WP_179933513.1 2464263..2464919(-) (vraR) [Streptomyces sp. Rer75]
GTGGGTGAGCGACGGGACGGAGCGGCGATCCGGGTGCTGCTCGTCGACGACCACCAGGTGGTGCGGCGCGGCCTGCGGAC
CTTCCTGGAGGTCCAGGACGACATCGACGTGGTCGGCGAGGGCTCGGACGGGGAGGAGGGCATCGCCCGGGCCGAGGAGC
TGCGCCCCGACATCGTCCTGATGGACGTCAAGATGCCCGGCATCGACGGCATCGAGGCGCTGCGCAAGCTGCGTGACCTG
GACAACCCGGCCCGGGTGCTGGTCGTGACGAGTTTCACCGAGAAGCGCACCGTGGTCCCCGCCCTGCGCGCGGGCGCCGC
CGGTTACGTCTACAAGGACGTGGACCCCGACGCCCTCGCGAGCGCCATACGGTCCGTCCACGCCGGGCATGTGGTGCTCC
AGCCCGAGGTGGCCGACGCGCTGCTCTCCCAGGACGAGGTGGGCGGCGGCCAGGGGCGCGGGGGCTCCCTCACCGACCGG
GAGCGGGAAGTGCTGGGGCTGATCGCGGACGGCCGGTCGAACCGGGAGATCGCACGCAGGCTCGTACTGTCCGAAAAGAC
CGTAAAGACACATGTGTCCAACATTCTTATGAAGTTGGACCTGGCCGACCGCACTCAGGCCGCACTCTGGGCGGTACGCC
ATGGAATCGGAGCATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

95.872

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

37.104

100

0.376

Multiple sequence alignment