Detailed information NTG0406322

Bioinformatically predicted

Overview

• Name: comGH
• Type: Machinery gene
• Locus tag: S9968_RS02350
• Genome accession: NZ_CP058666
• Coordinates: 409270..410244 (-)
• Length: 324 a.a.
• NCBI ID: WP_001008574.1
• Uniprot ID: Q8E232
• Organism: Streptococcus agalactiae strain S9968
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 404270..415244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S9968_RS02315 (S9968_100467)	pepA	404333..405400 (+)	1068	WP_001281323.1	glutamyl aminopeptidase	-
S9968_RS02320 (S9968_100468)	proC	405470..406240 (+)	771	WP_001865901.1	pyrroline-5-carboxylate reductase	-
S9968_RS02325 (S9968_100469)	-	406261..406926 (-)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-
S9968_RS02330 (S9968_100470)	-	406995..407450 (-)	456	WP_000905673.1	hypothetical protein	-
S9968_RS02335	-	407491..407628 (-)	138	WP_001865900.1	hypothetical protein	-
S9968_RS02340 (S9968_100471)	-	407687..407893 (-)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
S9968_RS02345 (S9968_100472)	-	408045..409238 (-)	1194	WP_000047534.1	acetate kinase	-
S9968_RS02350 (S9968_100473)	comGH	409270..410244 (-)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
S9968_RS02355 (S9968_100474)	comGG	410359..410730 (-)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
S9968_RS02360 (S9968_100475)	comGF	410708..411163 (-)	456	WP_000793378.1	competence type IV pilus minor pilin ComGF	Machinery gene
S9968_RS02365 (S9968_100476)	comGB	411160..412203 (-)	1044	WP_228308067.1	competence type IV pilus assembly protein ComGB	Machinery gene
S9968_RS02370 (S9968_100477)	comGA	412200..413081 (-)	882	WP_257151376.1	competence type IV pilus ATPase ComGA	Machinery gene
S9968_RS02375 (S9968_100478)	-	413254..413619 (-)	366	WP_000285373.1	DUF1033 family protein	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 37046.02 Da
• Isoelectric Point: 4.5224

>NTDB_id=406322 S9968_RS02350 WP_001008574.1 409270..410244(-) (comGH) [Streptococcus agalactiae strain S9968]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide

• Length: 975 bp

>NTDB_id=406322 S9968_RS02350 WP_001008574.1 409270..410244(-) (comGH) [Streptococcus agalactiae strain S9968]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterProScan.

• N-6 DNA Methylase (N6_Mtase) (70-303)

3D structure

• AlphaFold DB: Q8E232

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGH	Streptococcus mutans UA159	67.302	97.222	0.654
comGH	Streptococcus mutans UA140	67.302	97.222	0.654