Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GO004_RS18825 Genome accession   NZ_CP046591
Coordinates   3634014..3634658 (+) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain R31     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3629014..3639658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO004_RS18795 (GO004_18790) - 3629365..3629733 (-) 369 WP_014477834.1 hypothetical protein -
  GO004_RS18800 (GO004_18795) - 3629847..3629972 (-) 126 WP_003228793.1 hypothetical protein -
  GO004_RS18805 (GO004_18800) degQ 3630194..3630334 (+) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  GO004_RS18810 (GO004_18805) - 3630519..3631382 (+) 864 WP_043858576.1 polyprenyl synthetase family protein -
  GO004_RS18815 (GO004_18810) comX 3631384..3631605 (+) 222 WP_014480704.1 competence pheromone ComX -
  GO004_RS18820 (GO004_18815) comP 3631621..3633933 (+) 2313 WP_195727738.1 histidine kinase Regulator
  GO004_RS18825 (GO004_18820) comA 3634014..3634658 (+) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  GO004_RS18830 (GO004_18825) yuxO 3634677..3635057 (+) 381 WP_015714624.1 hotdog fold thioesterase -
  GO004_RS18835 (GO004_18830) mnhG 3635096..3635470 (-) 375 WP_003244302.1 monovalent cation/H(+) antiporter subunit G -
  GO004_RS18840 (GO004_18835) mrpF 3635454..3635738 (-) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  GO004_RS18845 (GO004_18840) mrpE 3635738..3636214 (-) 477 WP_029318490.1 Na+/H+ antiporter subunit E -
  GO004_RS18850 (GO004_18845) mrpD 3636220..3637701 (-) 1482 WP_003244432.1 Na+/H+ antiporter subunit D -
  GO004_RS18855 (GO004_18850) mrpC 3637694..3638035 (-) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  GO004_RS18860 (GO004_18855) mrpB 3638035..3638466 (-) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=405827 GO004_RS18825 WP_003220716.1 3634014..3634658(+) (comA) [Bacillus subtilis strain R31]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=405827 GO004_RS18825 WP_003220716.1 3634014..3634658(+) (comA) [Bacillus subtilis strain R31]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment