Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   HXS80_RS19875 Genome accession   NZ_CP058556
Coordinates   4600819..4601943 (-) Length   374 a.a.
NCBI ID   WP_030193970.1    Uniprot ID   A0A1V0UE85
Organism   Streptomyces sp. CB04723     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4595819..4606943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HXS80_RS19855 (HXS80_19855) - 4596556..4597224 (-) 669 WP_179182556.1 hypothetical protein -
  HXS80_RS19860 (HXS80_19860) - 4597407..4598081 (-) 675 WP_030331584.1 SigE family RNA polymerase sigma factor -
  HXS80_RS19865 (HXS80_19865) - 4598438..4599355 (-) 918 WP_030193976.1 A/G-specific adenine glycosylase -
  HXS80_RS19870 (HXS80_19870) - 4599660..4600409 (+) 750 WP_179182557.1 hypothetical protein -
  HXS80_RS19875 (HXS80_19875) disA 4600819..4601943 (-) 1125 WP_030193970.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  HXS80_RS19880 (HXS80_19880) radA/sms 4602024..4603436 (-) 1413 WP_179182558.1 DNA repair protein RadA Machinery gene
  HXS80_RS19885 (HXS80_19885) - 4603788..4605770 (+) 1983 WP_179182559.1 hypothetical protein -
  HXS80_RS19890 (HXS80_19890) - 4606002..4606868 (-) 867 WP_030299573.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40415.44 Da        Isoelectric Point: 5.1161

>NTDB_id=405526 HXS80_RS19875 WP_030193970.1 4600819..4601943(-) (disA) [Streptomyces sp. CB04723]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVHGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALTHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPNA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=405526 HXS80_RS19875 WP_030193970.1 4600819..4601943(-) (disA) [Streptomyces sp. CB04723]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGCAACGAGGCGCTGATGCGCGCCTCGCT
GAGCGCGGTCGCGCCCGGTATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAATACCGGTGGCCTGATCGTGC
TGGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGATTCGTGCTGGACGTCGAGTTCACGGCGACGCGCCTGCGA
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATGACGAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCTG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGCACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTGGCGGGCACGCTGTC
CGCCCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGCCTGGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGCCTCCTGGCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGGGAGCTGGTCGTCCGCGACTACGTCCCCGAGCCGACGGCGAAGCGGTCGCGGACGGTGGCCGA
GGCGCTGACGGAGCTGGACGCGCTGACCCACACCGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GTTCGCCCGAGACGCTGGACTCGGCGGTCTCCCCGCGGGGCTTCCGGCTGCTGGCGAAGGTCCCGCGGCTGCCGAACGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTCCAGGCGGTGGA
CGGCGTCGGCGAGGCGCGGGCCCGCAGTGTGCGGGAGGGGCTGTCGCGGCTGGCGGAGTCCTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0UE85

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

44.875

96.524

0.433