Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GOM46_RS02115 Genome accession   NZ_CP046525
Coordinates   412670..413359 (+) Length   229 a.a.
NCBI ID   WP_235083846.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 407670..418359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS02090 (GOM46_02075) gpsB 407729..408064 (+) 336 WP_321159627.1 cell division regulator GpsB -
  GOM46_RS02100 (GOM46_02085) - 408547..409725 (+) 1179 WP_235083844.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  GOM46_RS02105 (GOM46_02090) mapZ 409718..411157 (+) 1440 WP_006150220.1 cell division site-positioning protein MapZ -
  GOM46_RS02110 (GOM46_02095) gndA 411234..412658 (+) 1425 WP_006150418.1 NADP-dependent phosphogluconate dehydrogenase -
  GOM46_RS02115 (GOM46_02100) covR 412670..413359 (+) 690 WP_235083846.1 DNA-binding response regulator Regulator
  GOM46_RS02120 (GOM46_02105) mvk 413566..414444 (+) 879 WP_235083847.1 mevalonate kinase -
  GOM46_RS02125 (GOM46_02110) mvaD 414426..415379 (+) 954 WP_235083848.1 diphosphomevalonate decarboxylase -
  GOM46_RS02130 (GOM46_02115) - 415366..416379 (+) 1014 WP_235083849.1 phosphomevalonate kinase -
  GOM46_RS02135 (GOM46_02120) fni 416357..417358 (+) 1002 WP_235083850.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  GOM46_RS02140 (GOM46_02125) liaF 417453..418151 (+) 699 WP_235083851.1 cell wall-active antibiotics response protein LiaF -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26727.82 Da        Isoelectric Point: 7.4135

>NTDB_id=405055 GOM46_RS02115 WP_235083846.1 412670..413359(+) (covR) [Streptococcus infantis strain SO]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMIL
DHREELQGQLETIQRFAVSYIYKPVIIDDLVNRIAAIFRGRDFIDQHCSQMKVPTSYRNLRMDLENHTVYRGDEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=405055 GOM46_RS02115 WP_235083846.1 412670..413359(+) (covR) [Streptococcus infantis strain SO]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTAGAAGAGGGACAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGACTTGATTTTACTGAATG
CTCATCTAGGGGATATGACAGCTCAGGATTTTGCAGATAAGTTGAGTCGCACCAAGCCAGCGTCGGTTATCATGATTTTG
GATCATCGAGAAGAATTGCAAGGCCAACTTGAAACAATCCAGCGTTTCGCTGTTTCGTATATCTATAAACCAGTCATTAT
CGATGATTTGGTCAATCGTATTGCAGCGATTTTCCGAGGTCGGGACTTCATTGATCAACATTGTAGTCAGATGAAGGTTC
CTACATCCTATCGCAATCTGCGTATGGATTTAGAAAACCACACTGTCTATCGTGGCGATGAGATGATCGCTTTGACTCGG
CGTGAGTATGATCTTTTAGCAACCCTTATGGGAAGCAAAAAGGTCTTAACTCGTGAGCAGTTGCTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAAACCAATATTGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGACGTAAAAGGTCAAA
AGAGCTACATCAAAACTGTGCGTGGTGTTGGTTACACGATGCAAGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.053

99.563

0.459

Multiple sequence alignment