Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   GOM46_RS00830 Genome accession   NZ_CP046525
Coordinates   156431..158863 (+) Length   810 a.a.
NCBI ID   WP_235083678.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 151431..163863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS00800 (GOM46_00800) - 152245..152535 (+) 291 WP_235083672.1 MTH1187 family thiamine-binding protein -
  GOM46_RS00805 (GOM46_00805) - 152498..153256 (+) 759 WP_235083673.1 ABC transporter permease -
  GOM46_RS00810 (GOM46_00810) - 153291..154298 (+) 1008 WP_235083674.1 ABC transporter substrate-binding protein -
  GOM46_RS00815 (GOM46_00815) - 154298..155020 (+) 723 WP_235083675.1 ABC transporter ATP-binding protein -
  GOM46_RS00820 (GOM46_00820) - 155135..155695 (-) 561 WP_235083676.1 DUF308 domain-containing protein -
  GOM46_RS00825 (GOM46_00825) - 155966..156424 (+) 459 WP_235083677.1 CtsR family transcriptional regulator -
  GOM46_RS00830 (GOM46_00830) clpC 156431..158863 (+) 2433 WP_235083678.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GOM46_RS00835 (GOM46_00835) - 158937..159710 (+) 774 WP_235083679.1 NUDIX domain-containing protein -
  GOM46_RS00840 - 159760..159990 (-) 231 WP_006144770.1 hypothetical protein -
  GOM46_RS00845 (GOM46_00840) - 160257..160946 (+) 690 WP_235083680.1 hypothetical protein -
  GOM46_RS00850 (GOM46_00845) - 161074..161760 (+) 687 WP_235084132.1 YoaK family protein -
  GOM46_RS00855 (GOM46_00850) dusB 161813..162793 (-) 981 WP_235083681.1 tRNA dihydrouridine synthase DusB -
  GOM46_RS00860 (GOM46_00855) hslO 162780..163652 (-) 873 WP_235083682.1 Hsp33 family molecular chaperone HslO -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 90149.21 Da        Isoelectric Point: 6.3656

>NTDB_id=405032 GOM46_RS00830 WP_235083678.1 156431..158863(+) (clpC) [Streptococcus infantis strain SO]
MKYSKALRECIDSAFLVASRFGADYLESWHLLIAMANHSYSVAGATLNEFPYEIDRLEEVAVELTEANYSHKEDYQELPF
SYRLNVLMLEAEHVASVVHAKALGTEHLLYAILHDGNALATRILEKAGFSYEDQKDQVKIAGLRRNLEARAGWTKEDLKA
LRQRHRSVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDQEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIANGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVMIEEPSVADSMAILQGLKTIYEKHHHVQITDDAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESGLSPADKALMDGKWKQAAQLISKEQEAPVYKDVVKESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQEQAVSSISRAIRRNQSGIRNNKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQILDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
QDMQDVVKIMVKPLIASLAEKGIDLKLQASALKLLAQKGYDPEMGARPLRRTLQTEVEDKLAELLLTGELKEGKTLKIGV
KAGQLKFDIV

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=405032 GOM46_RS00830 WP_235083678.1 156431..158863(+) (clpC) [Streptococcus infantis strain SO]
ATGAAATATTCAAAAGCATTGAGAGAATGTATAGACAGTGCCTTTCTAGTGGCGAGTCGCTTTGGAGCAGACTACCTGGA
GTCTTGGCACCTACTGATTGCCATGGCCAATCATAGCTACAGTGTTGCTGGAGCAACTTTGAACGAGTTCCCGTATGAGA
TTGATCGTTTAGAGGAGGTCGCTGTTGAATTAACAGAGGCCAACTATAGCCACAAGGAAGATTATCAGGAACTCCCTTTT
TCTTATCGTTTAAACGTCTTGATGTTGGAGGCGGAACATGTTGCCTCCGTTGTACATGCAAAAGCATTGGGAACTGAGCA
CCTTCTCTACGCAATCTTGCATGACGGTAATGCTTTAGCTACTCGTATTTTGGAAAAAGCAGGTTTTTCTTATGAAGACC
AGAAGGACCAAGTCAAAATTGCTGGACTTCGTCGTAACCTTGAAGCGCGTGCTGGTTGGACAAAGGAAGATTTGAAGGCT
CTACGCCAGCGGCACCGCTCAGTAGCAGATAAGCAAAATTCTATGGCCAATATGATGGGCATGCCTCAAACTCCAAGTGG
TGGTTTGGAAGATTATACTCATGATCTCACAGAGCAAGCTCGTTCAGGCAAATTGGAGCCAGTTATCGGACGTGATCAAG
AAATCTCTCGTATGATTCAAATCTTGAGCCGTAAGACCAAAAACAATCCAGTTCTAGTTGGAGATGCGGGTGTTGGTAAA
ACAGCTTTAGCACTTGGCCTTGCGCAGCGAATTGCAAATGGAGATGTACCAGCTGAAATGGCTAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTGGTTGCAGGAACTCGCTTCCGTGGGGACTTTGAAGAACGTATGAATAATATCATCAAAGATA
TCGAGGAAGATGGTAAGGTTATCCTCTTTATCGATGAGCTTCATACCATTATGGGTTCAGGAAGTGGGATTGACTCGACC
TTGGATGCGGCCAATATCCTAAAACCTGCCTTGGCACGTGGAACTCTGAGAACTGTCGGAGCAACCACTCAGGAAGAATA
CCAAAAACATATCGAAAAAGACGCTGCCCTTTCTCGTCGCTTTGCTAAAGTGATGATTGAGGAGCCGAGCGTGGCTGATA
GTATGGCTATCTTACAAGGATTAAAGACAATCTATGAGAAGCACCACCATGTCCAAATTACAGACGATGCTGTCGAAACA
GCTGTTAAAATGGCGCATCGCTATTTGACAAGTCGTCACTTGCCAGACTCAGCGATTGACCTTTTGGATGAAGCAGCAGC
GACAGTCCAAAACAAATCGAAGCATGTGAAAGCAGACGAGTCAGGTCTATCTCCAGCTGATAAGGCCTTGATGGATGGCA
AATGGAAGCAAGCAGCGCAACTCATTTCAAAAGAGCAGGAAGCACCTGTTTACAAAGATGTAGTAAAAGAATCTGATATT
TTGACAACCTTGAGTCGCTTGTCAGGTATTCCAGTTCAAAAATTGACACAAACGGATGCCAAGAAGTATCTCAACCTTGA
AGCTGAGCTGCATAAACGTGTTATTGGACAAGAACAAGCTGTCTCTAGTATCAGTCGTGCCATTCGCCGAAATCAATCAG
GTATTCGCAATAACAAACGTCCAATTGGATCCTTTATGTTCTTAGGACCAACTGGTGTTGGTAAAACTGAATTGGCTAAG
GCTTTGGCAGAAGTTCTCTTTGATGACGAATCTGCCCTTATCCGCTTTGATATGAGTGAATACATGGAGAAATTTGCAGC
TAGCCGTCTCAACGGAGCTCCTCCAGGTTATGTAGGCTATGAAGAAGGTGGAGAGCTGACCGAGAAGGTTCGCAACAAAC
CATATTCAGTCTTGCTTTTTGACGAGGTAGAAAAGGCTCACCCAGATATCTTTAATGTTCTTTTGCAGATCTTGGATGAT
GGTGTCTTGACGGACAGTAAGGGCCGTAAGGTTGATTTTTCAAATACCATCATTATCATGACATCAAACCTCGGTGCGAC
AGCACTTCGTGATGATAAAACAGTCGGCTTTGGAGCTAAGGACATTCGTTTTGATCAAGAAAATATGGAAAAACGGATGT
TTGAAGAGCTAAAAAAGGCTTATCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTAGTCTTCCATAGCTTGTCAAGT
CAAGATATGCAGGACGTGGTTAAGATTATGGTCAAACCATTGATTGCAAGCCTGGCAGAAAAAGGGATTGACTTGAAACT
TCAAGCATCTGCCCTTAAGCTTCTGGCTCAGAAGGGCTATGATCCAGAGATGGGAGCTCGTCCACTACGCAGAACTTTGC
AAACAGAAGTAGAAGACAAACTAGCAGAACTCCTTCTTACAGGTGAACTGAAAGAAGGCAAGACACTGAAGATTGGTGTC
AAAGCTGGTCAATTGAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(370-441)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(718-798)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-135)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

AAA domain (Cdc48 subfamily) (AAA_2)

(540-711)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae D39

91.718

99.877

0.916
  clpC Streptococcus pneumoniae TIGR4

91.718

99.877

0.916
  clpC Streptococcus pneumoniae Rx1

91.718

99.877

0.916
  clpC Streptococcus mutans UA159

67.774

100

0.68
  clpC Streptococcus thermophilus LMD-9

66.38

100

0.668
  clpC Streptococcus thermophilus LMG 18311

66.258

100

0.667
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.903

100

0.522
  clpC Bacillus subtilis subsp. subtilis str. 168

44.704

100

0.448
  clpE Streptococcus mutans UA159

48.413

77.778

0.377

Multiple sequence alignment