Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GOM47_RS07975 Genome accession   NZ_CP046524
Coordinates   1571387..1572076 (-) Length   229 a.a.
NCBI ID   WP_235080457.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1566387..1577076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS07950 (GOM47_07945) fni 1566394..1567395 (-) 1002 WP_235080452.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  GOM47_RS07955 (GOM47_07950) - 1567379..1568386 (-) 1008 WP_235080453.1 phosphomevalonate kinase -
  GOM47_RS07960 (GOM47_07955) mvaD 1568373..1569326 (-) 954 WP_235080454.1 diphosphomevalonate decarboxylase -
  GOM47_RS07965 (GOM47_07960) mvk 1569308..1570186 (-) 879 WP_235080455.1 mevalonate kinase -
  GOM47_RS07970 (GOM47_07965) - 1570308..1571288 (-) 981 WP_235080456.1 N-acetylmuramoyl-L-alanine amidase family protein -
  GOM47_RS07975 (GOM47_07970) covR 1571387..1572076 (-) 690 WP_235080457.1 DNA-binding response regulator Regulator
  GOM47_RS07980 (GOM47_07975) gndA 1572088..1573512 (-) 1425 WP_045498904.1 NADP-dependent phosphogluconate dehydrogenase -
  GOM47_RS07985 (GOM47_07980) mapZ 1573588..1575036 (-) 1449 WP_235080458.1 cell division site-positioning protein MapZ -
  GOM47_RS07990 (GOM47_07985) - 1575049..1576206 (-) 1158 WP_235080459.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  GOM47_RS08000 (GOM47_07995) gpsB 1576695..1577021 (-) 327 WP_235080460.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26740.95 Da        Isoelectric Point: 8.6485

>NTDB_id=405005 GOM47_RS07975 WP_235080457.1 1571387..1572076(-) (covR) [Streptococcus oralis strain SOT]
MGKRILLLEKERNLARFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQAQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=405005 GOM47_RS07975 WP_235080457.1 1571387..1572076(-) (covR) [Streptococcus oralis strain SOT]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCGTTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTCCAGACGGATTATGACTTGATTTTACTGAATG
CTCATCTGGGGGATATGACGGCCCAGGATTTTGCAGATAAGCTGAGTCGAACAAAACCAGCCTCAGTAATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGCCCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAACTGGTAGCTCGTATTTCAGCGATTTTTCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACTGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTCTTGACTCGTGAGCAGCTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAACTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment